Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"relBE"”.
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Suitability of RelBE and MazEF toxin-antitoxin systems as antibacterial targets
… the tractability of targeting the TA systems RelBE and MazEF and these systems were found to be ubiquitous in clinical isolates of Pseudomonas aeruginosa and Staphylococcus aureus. A high-throughput in vitro screen to identify small molecule disruptors of RelBE was developed using the photonic …
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The prevalence of toxin-antitoxin systems and their tractability as novel antimicrobial targets
… target. Two TA systems, Axe-Txe and RelBE, were found to be common among the pathogenic bacteria surveyed and were therefore further investigated. A cell-based high-throughput assay was developed to screen for small molecules that induce toxin-dependent cell death in E. coli …