Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"regulatory lipids"”.
-
The regulation of yeast homotypic vacuole fusion and membrane trafficking events by sphingolipids, ergosterol, and lipid rafts
… process requires a minimal set of proteins and lipids in fully reconstituted systems, but in vivo fusion is a highly regulated process, with inputs from multiple signaling pathways. In live cells, membrane fusion requires the activity of SNAREs, small GTPases, chaperones, tethering complexes, …
-
Lipid composition and membrane physical parameters regulate priming and SNARE function in yeast vacuole membrane fusion
… SNAREs, membrane fusion also requires a set of regulatory lipids that includes ergosterol, diacylglycerol, phosphatidic acid and phosphoinositides. Although a lot is known about the SNARE protein machinery, the role of lipids and the lipid environment of the membrane are not clear. For long, …
-
The role of the Dgk1 and Pah1 in lipid interconversion on saccharomyces cerevisiae vacuole physiology, homeostasis, protein sorting and fusion
… vacuole, including a number of proteins and regulatory lipids. The deletion of the phosphatidic acid (PA) phosphatase gene Pah1, which converts PA in diacylglycerol kinase (DAG), was previously shown to produce a fragmented vacuole phenotype, greatly inhibit fusion and result in the vacuolar …
-
The regulation of yeast homotypic vacuole fusion by phosphatidic acid and diacylglycerol
… stages are well established, however the roles regulatory lipids at the membrane play are still unclear. Many specific regulatory lipids localize to the site of fusing vacuoles termed the “vertex ring” implying an important role for them throughout the fusion process. It has been shown that the …
-
Novel lipid regulation of vacuolar fusion in saccharomyces cerevisiae
… well established that enrichment of specific regulatory lipids leads to recruitment and activation of the fusion machinery. Additionally these lipids are modified by specific kinases, phosphatases and lipases allowing regulation of the different stages of fusion. Furthermore, some regulatory …