Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 2320 for “"regulators"”.
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Novel Regulators of Somatic Cell Reprogramming
… of SC signature genes further identified regulators of transition to the stabilization phase, while screening of the same signature in iPS cells revealed a distinct subset of genes required for maintenance of pluripotency. These studies reveal that the acquisition and subsequent …
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Regulators of autophagy in Leishmania major
Autophagy is a conserved lysosomal degradation pathway for recycling long-lived proteins and organelles that is thought to be required for life cycle progression and virulence of Leishmania. ATG8 is a ubiquitin like protein that is required for the formation of autophagosomes, and Leishmania …
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Use of Growth Regulators on Vegetables
Made available in DSpace on 2014-12-14T15:45:33Z (GMT). No. of bitstreams: 1 7821225.pdf: 4799676 bytes, checksum: 23e1bf51de8d28a39d3b808ba7667de6 (MD5) Previous issue date: 1978
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Investigation on regulators in quantum electrodynamics
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Physics, 1958.
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Transcriptional regulators in stem cell biology
… enacted by proteins including epigenetic regulators and transcription factors, determines cell fate. However, the functions of transcriptional regulators of stemness may differ in normal and transformed cells. In this thesis, I describe two transcriptional regulators of stemness and their …
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Input filter compensation for switching regulators
… can also be extended to other types of switching regulators.
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Advanced Control Schemes for Voltage Regulators
The microprocessor faces a big challenge of heat dissipation. In order to enhance the performance of the microprocessor without increasing the heat dissipation, the leading microprocessor company, Intel, uses several methods to reduce the power consumption. Theses methods include enhanced sleep …
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NOVEL REGULATORS OF GPVI-MEDIATED PLATELET ACTIVATION
… the focus of this thesis is to identify novel regulators of GPVI-mediated platelet signaling. Phosphoinositide 3-kinase (PI3K) is an important signaling molecule that is activated downstream of various receptors including GPVI upon platelet activation. PI3K activation leads to the generation of …
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Puppets in chaos: airlines, regulators and strings
An examination of the relationships between competition and the deregulation and liberalisation of the US and European air transport sectors reveals that the structure of the air transport sector is undergoing a number of significant changes: a growing number of airlines are entering into …
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Multifunctional Regulators of Cardiac Disease and Development
… MEF2 proteins are widely known as essential regulators of development of various tissues such as striated muscle and brain. Based on expression patterns of Mef2 genes and skeletal defects present in Mef2c +/-; Mef2d +/- mice, I hypothesized that MEF2is an important regulator of skeletogenesis …
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Pharmacological regulators of T cell calcium stores
… look at the effects of various pharmacological regulators of T cell calcium stores. At the start, the effort was directed at the regulation of the microsomal calcium A TPases, considering these are perhaps the most essential mediators of intracellular calcium storage. Thapsigargin (TG) and …
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CHARACTERIZATION OF MITOTIC REGULATORS ACM1 AND CDC14
Mitotic exit and cytokinesis are driven by a complex set of processes that serve to
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MarR Family Transcriptional Regulators from Streptomyces coelicolor
A family of transcriptional regulators that ubiquitously exists in prokaryotes is the multiple antibiotic resistance regulator (MarR) family. These transcriptional regulators participate in many cellular processes and can provide valuable knowledge about transcriptional regulation in response to …
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A systematic approach for cataloging mTORC1 regulators
… Toward generating a complete list of mTORC1 regulators, we developed a strategy to identify them by CRISPR-Cas9 FACS-based screening. As a proof-of-principle screen, we first identified negative regulators of the mTORC1 pathway. Then, we adapted the technique to uncover positive regulators of …
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Beta 3 integrins : negative regulators of angiogenesis
A method was developed to isolate and purify primary murine endothelial cells from lung tissue (MLEC). The cells generated by this method were characterized by immuno-fluorescence detection and FACS analysis and expressed specific antigens including PECAM-1, ICAM-1, ICAM-2, VCAM-1 and VE-cadherin. …
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High Frequency, High Current Density Voltage Regulators
As a very special DC-DC converter, VRM (Voltage Regulator Module) design must follow the fast-developing trend of microprocessors. The design challenges are the high current, high di/dt, and stringent load-line requirement. When the energy is transferred from the input of a VRM, through the VRM, …
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Improvements in integrated high-quality rectifier-regulators
The integrated high-quality rectifier-regulators [1] are not practical for universal input voltage and wide load range applications because of high bulk-capacitor voltage stress at lighter loads. This load-dependent characteristic of the bulk-capacitor voltage is due to the integration of a …
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Chromatin Regulators of MYC Oncoprotein Activity in Cancer
… yielded chromatin complexes and epigenetic regulators. In this thesis, we investigated two MYC-interacting complexes and defined the chromatin landscape of the MYC interactome. We characterized the novel interaction of MYC and the G9a histone methyltransferase and demonstrated their …
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Plant growth regulators: an alternative to frequent mowing
… to determine if the application of Plant Growth Regulators (PGR's) to frequently mowed semi-improved areas can minimize the total annual mowing costs at Naval Air Station Cecil Field, Florida and Naval Air Station Jacksonville, Florida. The highest potential savings are in areas where the …
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