Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"regulation of vascular tone"”.
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Methyl esterification of fatty acids and eicosanoids with a novel reagent trimethylsilyldiazomethane for analysis by gas chromatography-mass spectrometry
… water solubility that belong to the lipid class of bio-organic compounds and can be utilized as a source of energy by the body or as precursors to oxidized compounds that have roles in inflammation and in the regulation of vascular tone. The prostaglandins are naturally occurring 20-carbon …
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The role of AMP-activated protein kinase in endothelial VEGF signalling
The endothelium acts to maintain vascular homeostasis, including the regulation of vascular tone, blood fluidity and coagulation. Endothelial dysfunction, a condition largely characterised by reduced NO bioavailability, is an important feature associated with the aetiology of several …
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Effects of combustion derived air pollution on vascular and fibrinolytic function in man
… exposure to air pollution and increased cardiovascular morbidity and mortality. These associations are strongest for fine particulate matter (PM), of which particulates from the combustion of fossil fuels are an important component. In Europe, the contribution to urban PM from diesel emissions …
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Coronary Reactive Hyperemia
Introduction: The mechanism of post ischemic reactive hyperemia is still unknown but now thought to be multifactorial and perhaps involving purinergic signalling. Purines such as ATP and ADP have recently been discovered to play a vital role in the regulation of vascular tone. We postulated that …
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Regulation of the nitric oxide receptor, soluble guanylyl cyclase
… nitric oxide (NO) and regulates a great number of important physiological functions. Surprisingly, despite the wellappreciated roles of this enzyme in regulation of vascular tone, smooth muscle cell proliferation, platelet aggregation, renal sodium secretion, synaptic plasticity, and other …
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Integrated Microvascular Flow Regulation and the Impact of Metabolic Disease
The growing prevalence of metabolic diseases poses a significant challenge to public health. One of the steadily emerging challenges facing individuals suffering from chronic metabolic disease is the development of cardiovascular diseases. While cardiovascular diseases may affect any part of the …
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Design, Synthesis and Pharmacological Characterization of Novel Calcitonin Gene-Related Peptide Receptor Antagonists
… from tissue-specific alternative splicing of the primary RNA transcript of the calcitonin gene. CGRP is widely distributed throughout the central and peripheral nervous systems and is involved in wound healing, inflammatory responses, nociception, appetite suppression, gastric emptying, …
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MAPK and pro-inflammatory mediators in the walls of brain blood vessels following cerebral ischemia
… disability [1, 2]. There are two major types of stroke: ischemic and hemorrhagic stroke. Both are associated with disruption of blood flow to a part of the brain with rapid depletion of cellular energy and oxygen, resulting in ionic disturbances and eventually neuronal cell death [3]. The …