Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 254 for “"regenerative medicine"”.
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MSC DERIVED EV IN REGENERATIVE MEDICINE
One of the greatest requirements of modern medicine is the ability to treat patients suffering from osteoarthritis (OA) and bone fractures. Currently, there is no long-term therapy for OA; symptoms can be managed with anti-inflammatories and analgesics until they worsen to the extent that the …
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APPLICATIONS OF MICROARRAYS AND STEM CELLS FOR REGENERATIVE MEDICINE
… a potential resource for cell-based therapy and regenerative medicine. Understanding the genes that govern the special properties of stem cells has implications for both stem cell biology and regenerative medicine. This information will ensure the quality of the cells, the specificity of …
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Regenerative medicine of the skin: Quantitative and qualitative analyses
Contains fulltext : 212646.pdf (Publisher’s version ) (Open Access)
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In Vitro Models of Cellular Dedifferentiation for Regenerative Medicine
… can be made by dedifferentiation of adult cells. Regenerative medicine aims to utilize the potential of stem cells to treat disease and injury. The ability to create stem cell lines from a patient's own tissues allows for transplantation without immunosuppressive therapy as well as …
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Centrifugal recovery of embryonic stem cells for regenerative medicine bioprocessing
… the potential of embryonic stem (ES) cells as a regenerative medicine, it is crucial that economical, robust and scalable bioprocesses be established. Because bioprocesses irrevocably define the safety and efficacy of any biologically derived product, an understanding of the the impact of the …
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Engineering Liver and Cardiac Models for Drug Development and Regenerative Medicine
… Tissue engineering is also increasingly used for regenerative medicine and for modeling of metabolism and physiology. However, there are material challenges associated with cellular organization, tissue integration, vascularization, and structural properties. Liver tissue engineering approaches …
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Towards embryonic scaffolds for regenerative medicine. Glycosaminoglycans, effector molecules and collagen
Contains fulltext : 182800.pdf (Publisher’s version ) (Open Access)
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COLLAGEN AND ANTIOXIDANTS FROM SEA URCHINS: WASTE VALORIZATION CHALLENGES TOWARDS REGENERATIVE MEDICINE
… biomaterials suitable for tissue engineering and regenerative medicine. Future research should focus on extending the antioxidant activity to CollMA-UV and Coll-P, which has been demonstrated by adding PHNQs for Coll- PHNQ development, and in vivo evaluations to validate the efficacy and …
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REGENERATIVE MEDICINE STRATEGIES FOR ENDOMETRITIS IN REPRODUCTIVE MARES:IN VITRO AND IN VIVO STUDIES
… isolated extra-foetal adnexa as sources of regenerative medicine. Platelet rich plasma (PRP) was also examined as further alternative approach. The initial phase of research involved in vitro studies: 1) Wharton’s jelly-derived conditioned medium (WJ-CM) and PRP were investigated in …
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Investigation of a pancreatic derived progenitor cell population for use in regenerative medicine
… deriving a functional cell population for use in regenerative medicine strategies. They demonstrate that this is achievable using intravenous administration of adult cells to regenerate pancreatic tissue. Critically, they enhance our understanding of the mechanisms relating to such repair and …
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The use of health economics in the early evaluation of regenerative medicine therapies
The aim of this thesis is to help the RM industry avoid misguidedly investing in technologies that are unlikely to be cost-effective and reimbursed by healthcare providers. Health economics provides the tools to demonstrate value for money. These tools are typically used by healthcare providers to …
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Tissue engineering the anterior cruciate ligament : a regenerative medicine approach in orthopaedic surgery
Anterior cruciate ligament (ACL) injuries affect over 200,000 Americans yearly, and many occur in young athletes. Current treatment options include tendon autografts and cadaveric allografts. However, these approaches often lead to secondary medical problems, such as donor-site morbidity and immune …
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Building blocks for regenerative medicine : vascularized models and immunomodulation to engineer hepatic cell therapies
… primary human hepatocyte sourcing is the loss of regenerative potential of the cells ex vivo.
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Making Stem Cell Niches: An Ethnography of Regenerative Medicine in Scotland and the United States
… within national projects of translational regenerative medicine. This analysis both draws upon and contributes to the social studies of biomedicine, reproductive studies and science and technology studies. I examine how stem cell scientists, involved in an international research initiative, …
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Development and characterisation of a heparinised fibrin hydrogel as a delivery vehicle for regenerative medicine
… is an attractive hydrogel candidate for regenerative medicine due to its inherent biocompatibility, biodegradability, and clinical approval. It is the precursor protein cleaved by the protease thrombin that polymerises into a fibrous network known as fibrin. The present study sought to …
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Characterization of Biomaterials for Regenerative Medicine via Computational Fluid Flow Analysis of Dynamic Contrast Enhanced – Magnetic Resonance Imaging (DCE-MRI) Images
… advancements have been made within the field of regenerative medicine over the last few decades with the goal of creating biological substitutes to mimic tissue for research and wound healing purposes. Simply put, regenerative medicine works by understanding and then manipulating the processes by …
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HUMAN WHARTON'S JELLY MESENCHYMAL STEM CELLS (WJ-MSCs): CHARACTERIZATION AND PROPERTIES
… prospective and potential application in regenerative medicine. MSCs are defined as immature cells with the ability to self-renew and differentiate into specialized cells belonging to different lineages. Due to their high proliferative potential, MSCs can be rapidly expanded in vitro when …
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