Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"refractoriness"”.
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An investigation of low expansion cordierite-zirconia bodies
… to determine to what extent the ultimate refractoriness and use temperature could be increased by the addition of zirconia without increasing the thermal expansion above 4.0 x 10⁻⁶ cm./cm./°c. A procedure has been presented for making the compound cordierite. Several raw batch compositions …
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Discovery of Dihydroartemisinin and Dasatinib Drug Combination to Cure Pooroutcome BCR-ABL+ Acute Lymphoblastic Leukemia
… comparisons indicated that IL7 imparts chemo-refractoriness by initiating IL7-pSTAT5-c-MYC signaling. Interestingly, IKAROS haploinsufficiency, which has been previously associated with poor clinical prognosis in patients with Ph+ ALL, was recently demonstrated to directly de-repress c-MYC …
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Examining The Role Of Lysyl Oxidase Enzymes In Atrial Fibrillation Induced By Volume Overload
… increased AF susceptibility, decreased atrial refractoriness (AERP), elevated left atria (LA) fibrosis, and macrophage infiltration 2-fold compared to sham mice. LOXL2 inhibitor PXS-5382 reduced AF inducibility, shortened AF duration and attenuated fibrosis without affecting AERP. In contrast, …
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Deciphering host-parasite molecular networks mediating resistance to toxoplasma gondii
… toxoplasmosis between rats and humans, and the refractoriness of the LEW rat to T. gondii infection when compared to the susceptible BN rat, provide an opportunity to use the two rat strains as models for deciphering host molecular mechanisms that mediate resistance to T. gondii. This can …
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Arrhythmias in Pulmonary Hypertension
… prolonged repolarization, and increased AV nodal refractoriness, offering mechanistic insights into arrhythmia development. These findings underscore the need for future research into the benefit of prophylactic arrhythmia screening and intervention in IPAH patients with right atrial dilation, and …
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Evaluating The Therapeutic Efficacy of Restoring Wild-Type P53 Activity In P53-Mutant Tumors
… have been shown to be remarkably predictive of refractoriness to treatment, resulting in poor outcome. Consequently, the development of p53 pathway activating agents is rapidly evolving and gaining more attention in cancer therapeutics research, with several small molecule compounds currently in …
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Deoxidation mechanisms in liquid steel.
… interfacial energy characteristics; the refractoriness of the oxidation products and intermediate compounds; and the degree of turbulence experienced by the melt. Explanations have been postulated which elucidate the behaviour of the different deoxidants, as not all displayed the whole …
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Postpartum ovarian activity and response to progestagen treatment in rustic beef cows (Spanish Retinta) underfed to simulate their typical ranging conditions
… Retinta cows in this study exhibited a marked refractoriness to estrous induction/synchronization treatment and had a prolonged postpartum anestrus either at low or adequate BCS levels. Further, undernutrition prolonged the postpartum interval to estrus and conception.</p>
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A study of the gelation of air-setting refractory mortars
… the gelation but these tended to lower the refractoriness of the mortar.</p> <p>A study was made of the base exchange capacities of the dry materials and the material with the highest base exchange capacity was found to contribute more to the gelation than did one without so many …
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The neuroendocrine mechanism of reproductive photorefractoriness in the ewe
… neuroendocrine mechanisms of reproductive photorefractoriness using pharmacological and neurosurgical approaches. Ovary-intact (INTACT), ovariectomized (OVX) and ovariectomized estradiol-treated (OVX + E$\sb2$) ewes were subjected to 3 different photoperiodic regimens which resulted in …
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The use of cultured cells with defects of citrulline metabolism in diagnosis and in the study of intercellular communication
… by TPA than the original ASS⁻/ASL⁻ co-cultures. Refractoriness to TPA occurred following prolonged treatment with high concentrations of TPA. Retinoic acid and other retinoids also inhibited junctional communication, and the inhibitory effects of retinoic acid and TPA were additive. The …
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A Study of Ionic Permeability Changes Underlying Excitation in Myelinated Nerve Fibers of the Frog
… potential, ionic exchanges during activity, refractoriness, and other phenomena as sociated with excitation and with conduction of the action potential. Good agreement between the theoretical computations and the experimental observations has established the validity of the voltage-clamp …
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Tinnitus and Decreased Subcortical and Cortical Inhibition
… gating and/or a change in the recovery time, or refractoriness, of auditory evoked responses in individuals with tinnitus. The strong predictive influence of age on the 〖"P1" 〗_"lat ratio" indicates that increasing age reduced sensory gating above and beyond the effects of tinnitus. Potential …
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Applications of next-generation technologies in the diagnosis of haematological diseases and cancer
… characteristics, including age and chemo-refractoriness. Mutations introduced as part of the SHM process in B-cells are present throughout the genome, including in patients with unmutated IgHV genes. Regions of localised hypermutation are present in CLL, with a number affecting genes …
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Hydrothermal treatment of sewage sludge under oxidative and nonoxidative conditions
… these in the floc structure. Therefore, greater refractoriness to the oxidation was observed on those fractions located more externally to the cells. Moreover, the analysis of the molecular size distribution of the biopolymers during wet oxidation showed that the larger molecules were degraded by …
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Allergen-induced change in airway responsiveness to direct and indirect stimuli in mild atopic asthmatics
Methacholine (MCh) and mannitol challenges are tests used to assess airway responsiveness. It has been shown that airway responsiveness to direct bronchoconstrictors like MCh tends to increase following exposure to allergen but the response to mannitol an indirect stimuli, is not known. …
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Clozapine in Treatment-Resistant Schizophrenia (TRS): improving access and utilisation
… where it is initiated as soon as treatment refractoriness is ascertained. When we can fully utilise clozapine in patients with TRS, then we can turn our attention to the 40-50% of patients who have less than satisfactory response to clozapine, or those patients deemed as ultra treatment …
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The Role of PGRP Proteins in Innate Immunity Pathways in the Malaria Vector Anopheles gambiae
… a parasite infection leads to a very strong refractoriness phenotype: most of the midgut-invading ookinetes are eliminated (presumably by lysis) and the remaining of the ookinetes are melanized. We thus assume that under wild-type infection conditions the parasite is either evading …
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HIV-Polymyositis progressing to inclusion body myositis: clues to earlier diagnosis
… median period of 22 months (range: 8-53). Drug refractoriness should alert the clinicians of this clinical progression from HIV-PM to HIV-IBM. A relatively high CK but less than 15 times the upper limit of normal is another clue for this clinical entity. In this study all the patients who had …
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Polymer-cementové kompozity pro žárovzdorné aplikace
Táto bakalárska práca sa zaoberá prípravou vysoko pevnostných polymér-cementových kompozitov na báze vápenato hlinitanového cementu a polyvinylalkoholu. MDF kompozity sú zaujímavé svojimi mechanickými vlastnosťami, ktoré prevyšujú pevnosti bežných materiálov na báze cementu a anorganických spojív. …
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