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Showing 1 to 20 of 656 for “"reductase"”.
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Biliverdin reductase in cardiovascular inflammation
Biliverdin Reductase (BVR) functions downstream of Heme Oxygenase 1 (HO-1) in the process of heme degradation and catalyses the reduction of biliverdin to bilirubin. For over thirty years, BVR was regarded as rather a trivial enzyme whose only known function was to aid heme disposal. Over the last …
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Nitrate reductase in apple trees
Factors affecting the in vivo nitrate reductase assay were investigated in order to optimize the assay conditions for various tissues of MM 106 apple trees. Optimum concentrations of nitrate and phosphate for in vivo nitrate reductase activities ranged from 50 to 100 mM and were tissue-specific. …
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Evolution of copper-containing nitrite reductase
Copper-containing nitrite reductase (NiR) is a homotrimer of two cupredoxin domains and catalyzes the single electron reduction of NO2- to NO during dissimilatory denitrification. To investigate the evolution of NiR, methods of mutagenic library generation and high-throughput variant screening from …
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A study of succinic dehydrogenase, indole acetic acid oxidase, nitrate reductase and cytochrome c reductase in Hygrophorus Conicus
… (succinate : phenazine methosulfate oxidoreductase, EC 1.3.99.1) of Hygrophorus conicus, a member of a class of fungi known as basidiomycetes, was found to be stimulated by nitrate. Two substances were tested as electron acceptors in the measurement of succinic dehydrogenase activity. Of …
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Studies on the cytochrome bd-type oxygen reductase superfamily and the discovery of a novel nitric oxide reductase
… respiration on the planet– the bd-type oxygen reductase superfamily and the heme-copper oxidoreductase superfamily. The bd-type oxygen reductases are present in bacteria and archaea and catalyze the 4-electron reduction of oxygen to water. Electrons from membrane bound quinols first reduce a …
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Acetylation regulates Thioredoxin Reductase activity and oligomerization
… cancer to cardiovascular disorders. Thioredoxin reductase (TrxR) is the key enzyme in the Trx system and contains the 21st genetically encoded amino acid, selenocysteine (Sec). There were multiple experimentally identified TrxR acetylation sites with an unknown effect on TrxR activity. My thesis …
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Dihydropteridine Reductase from Man and the Rat
Dihydropteridine reductase has been purified from rat liver and human brain tissue samples by affinity chromatography using sodium 1,2-naphthoquinone-4-sulphonate as the ligand. The rat liver dihydropteridine reductase was purified over 960 fold over the original supernatant and Km's for the two …
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Hydrogenase and Thiosulfate Reductase From Desulfovibrio Vulgaris
Made available in DSpace on 2014-12-09T22:04:19Z (GMT). No. of bitstreams: 1 6915316.pdf: 3269181 bytes, checksum: b920d3815a77bc82f7b7e97e54f1ee61 (MD5) Previous issue date: 1969
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Mycothiol disulfide reductase as a drug target
Includes abstract. Includes bibliographical references (leaves 154-171).
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Investigations of the inhibition mechanisms of human ribonucleotide reductase by gemcitabine-5'-diphosphate and saccharomyces cerevisiae ribonucleotide reductase by Sml1
Ribonucleotide reductases (RNRs) catalyze the conversion of nucleotides to deoxynucleotides supplying the dNTPs required for DNA replication and DNA repair. Class I RNRs require two subunits ([alpha] and [beta]) for activity. The [alpha] subunit binds the substrates and the allosteric effectors …
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Regulation of Human Carbonyl Reductase 3 (CBR3) Expression
Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové Katedra biochemických věd Kandidát Mgr. Petra Malátková Školitel Prof. Ing. Vladimír Wsól, Ph.D. Název disertační práce Regulace exprese lidské karbonylreduktasy 3 (CBR3) Regulace exprese lidské karbonylreduktasy 3 (CBR3) byla až …
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Characterization of ribonucleoside diphosphate reductase from Thermoplasma acidophila
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1997.
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Studies on the Regulation of Hepatic Hmg Coenzyme a Reductase and the Production of Anti-Hmg-Coenzyme a Reductase Monoclonal Antibodies
… purpose of studying the regulation of HMG-CoA reductase.
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Investigations on the Reaction Mechanism of Xenobiotic Reductase A
Xenobiotic reductase A (XenA) from Pseudomonas putida 86 is a member of the Old Yellow Enzyme family of FMN containing enzymes. It catalyzes the NADH/NADPH dependent reduction of various substrates, including 2-cyclohexenone, coumarin, 7- and 8-hydroxycoumarin in a two-step mechanism consisting of …
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자궁내막증 자궁내막에서의 세포증식 증가와 thioredoxin reductase-1 발현의 증가
… 자궁내막 용종의 발생율 및 세포의 증식도, Bcl-2 단백질과 thioredoxin reductase-1 (TrxR-1)의 발현 정도를 알아보고자 하였다. 연구대상 및 방법 : 복강경과 자궁경을 시행받은 총 631명의 불임 여성 중 자궁내막증을 가진 434명을 실험군으로 자궁내막증이 없는 197명을 대조군으로 하여 자궁내막 용종의 발생율을 조사하였다. 이후 양군에서 얻은 자궁내막조직으로 Ki-67, Bcl-2 단백질과 TrxR-1의 발현을 알아보기 위해 면역조직화학염색법으로 염색한 후 컴퓨터 프로그램 (Imagepro …
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Biochemical characterization of C-family heme copper oxygen reductase
Heme copper oxygen reductases (HCOs) are key enzymes for aerobic respiration. As a terminal electron acceptor, HCO catalyzes the sequential transfer of four electrons from reduced cytochromes c on the P-side of the membrane, and four protons from the cytosol on the N-side, to molecular O2 bound at …
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The Methyl-Coenzyme M Reductase System in Methanobacterium Thermoautotrophicum
Made available in DSpace on 2014-12-14T07:14:45Z (GMT). No. of bitstreams: 1 7804010.pdf: 4777401 bytes, checksum: fc91aa47a8e3f2b0af685858c4c06d47 (MD5) Previous issue date: 1977
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Ubiquitin E3 ligase mediated regulation of HMG-CoA Reductase
… I molecules. The ER-resident enzyme HMG-CoA reductase (HMGCR) catalyses the rate-limiting step in the cholesterol biosynthesis pathway and is targeted therapeutically by statins. To maintain cholesterol homeostasis, the expression of HMGCR is tightly regulated by sterols transcriptionally and …
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