Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 72 for “"red-shifted"”.
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Synthesis of novel red-shifted phthalocyanines
We prepared four types of red-shift phthalocyanines: 2,9,16,23-tetra(hetp-t-1 -enyl) phthalocyanine; 2,9,16,23-tetrachloro-3,10,17,24-tetra(3-methoxypro1p --y nyl) phthalocyanine; 3,4,12,13,2 1,22,30,3 l-octa(alkyny1) and octa(alkeny1) naphthalocyanines. It was found that the each conjugated …
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Noninvasive optical inhibition with a red-shifted microbial rhodopsin
… engineering, and implementation of a new red-shifted cruxhalorhodopsin, Jaws, derived from Haloarcula salinarum (strain Shark), which mediates three-fold higher red light-induced photocurrents than other inhibitory opsins. I describe the design process involved in engineering Jaws, as well …
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The synthesis and in vivo evaluation of chemically modified siRNAs that contain red-shifted internal azobenzene derivative spacers for selective and tunable photocontrol of activity without UV light
… at the ortho position on the azobenzene to red-shift the π→π* of the N=N double bond out of the UV portion of the electromagnetic spectrum into the visible region, allowing the siRNA to be inactivated with red light, which is less toxic and through constant exposure inactivates the siRNA for …
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Outer-core emission spectroscopy of the heavy alkaline-earth metals
… spectra are found to be anomalously broad and red-shifted with regard to XPS core positions. With the help of data from complementary core-level spectroscopies, a model for both the creation and the annihilation of these core configurations is inferred.
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Development of Endoplasmic Reticulum Targeted Probes and Red Fluorescent Probes for Detecting Zinc
… sensors by introducing the first generation of red-shifted cpFP Zn<sup>2+</sup> sensors. We demonstrate that not only can these Zn<sup>2+</sup> sensors be targeted to the ER, but they can functionally be used to estimate labile ER Zn<sup>2+</sup> concentration. We also show that red-shifted cpFP …
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Near infrared transient absorption spectra of photolyzed myoglobin at low temperatures
"We have measured the transient absorption spectrum of photolyzed sperm whale carboxymyoglobin as a function of temperature and time after photolysis. Our measurements extend from 60K to 220K and from three microseconds to thirty seconds. We see an absorption band near 758 nm which is known as band …
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A Developed and Characterized Orthotopic Rat Glioblastoma Multiforme Model
… have transduced F98 rat glioma cells to express red-shifted firefly luciferase, which will facilitate longitudinal tumor monitoring in vivo through bioluminescent imaging. I have characterized their response to H-FIRE relative to DI TNC1 rat astrocytes. I have demonstrated the presence of the …
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Homology Cloning, Heterologous Expression and Characterization of A New Channelrhodopsin
… the channelrhodopsin in HEK293 cells and measured light-induced currents to assess their kinetics and action spectrum. Based on the primary structure, kinetics of light-induced photocurrents in HEK293 cells, and action spectrum maximum of 520 nm near that of the two previously found …
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Photochemical synthesis and characterization of mono- and bi-nuclear tungsen tetracarbonyl complexes of 2,2'-biquinoline and 2,3-bis(2- pyridyl) pyrazine
… and the THF was then replaced by the desired ligand. All complexes were characterised by a combination of infrared, UV-visible, *H NMR, mass spectroscopy and elemental analysis. Infrared spectra indicate that the complexes have approximately Cz* local symmetry. The absorption spectra of …
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Characterization of cpeY and cpeZ mutants in Fremyella diplosiphon strain UTEX 481
… and <em>cpeZ</em> deletion mutants and compared them with wild type (WT). Both <em>cpeY</em> and <em>cpeZ </em>mutants generated much less PE than WT as well as assembling much less PE into the PBS. PE purified from <em>cpeY</em> mutant had phycocyanobilin on alpha-PE in place of PEB. The …
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Molecules and materials for the optical detection of explosives and toxic chemicals
… and poly(fluorene)s. These materials displayed red-shifted absorption and emission spectra, large Stokes Shifts, as well as long excited state lifetimes.
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Synthesis of Highly Ordered Polymer Nanostructures Based on Polyphenylene Vinylenes (PPVs)
… modulation. Thin film fluorescence showed broad, red-shifted emission for septamer PPV copolymers with tetraethylene glycol linkers, which suggests stronger inter-chromophore interactions in the solid state. Such low energy complexes were not observed in smaller PPV chromophore polymers. …
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Photoluminescent energy transfer from poly(phenyleneethylene)s to a series of dyes
… to identify efficient energy acceptors with red-shifted emissions relative to donor emission. A dialkoxy substituted poly(phenylene- ethylene) (PPE) and its pentiptycene derivative were used as the energy donor, and xanthene, cyanine, phenoxazine, and squaraine dyes were utilized as energy …
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New optical materials containing isobenzofuran
… route to integrate isobenzofuran into near-infrared donor-acceptor type fluorophores. These dyes, the IBF-NIADs, exhibit red-shifted absorption and emission over corresponding isothianaphthene containing dyes, thus highlighting the effective proquinoid nature of isobenzofuran. With the …
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Optogenetic disruption of memory-drive, oculomotor behavior in the non-human primate
… is critical for executing saccades to remembered locations. FEF neurons increase their firing rate during the three epochs of the memory-guided saccade task: visual stimulus presentation, the delay interval, and motor preparation. It is unclear, though, whether FEF activity during each epoch …
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Synthesis and characterization of binuclear and unsymmetrical phthalocyanines
… phthalocyanine sharing a naphthalene ring is red shifted compared to binuclear phthalocyanine sharing a benzene ring. The compounds are shown to form the liquid crystal mesophases at room temperature.</p> <p>The unique unsymmetrical phthalocyanines with steric hindrance tetraphenyl or …
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Through barrier detection using surface enhanced spatially offset Raman spectroscopy
… beneath the surface or through samples obscured by an opaque barrier.;Spatially offset Raman spectroscopy provides a means of overcoming the limitation associated with conventional Raman spectroscopy since it is capable of providing a unique chemical fingerprint of the analyte understudy, …
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Electronic spectroscopy of flavins in a cryogenic 22 - pole ion trap
… and electronic properties. Precisely, all measured spectra are assigned to S1-S0 (pi pi*) transitions. The experimentally extracted S1 origin transitions are either blue- or red-shifted to those obtained for neutral flavins, which is connected to a decrease and increase in the intermolecular …
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Towards The Development Of Intrinsically Fluorescent Unnatural Amino Acids For In Vivo Incorporation Into Proteins
… I will demonstrate our synthetic efforts to red-shift Acd’s emission and our preliminary efforts to incorporate these red-shifted Acd derivatives using a newly evolved synthetase. While our current efforts to incorporate Acd derivatives are unsuccessful, we have a crystal structure of the …
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Independent two-color optogenetic excitation of neural populations
… optical excitation in blue (470 nm) and red (625 nm) channels. Zero post-synaptic crosstalk is demonstrated in acute murine slice, using two novel channeirhodopsins identified from a systematic screen of 80 naturally occurring, previously uncharacterized opsins in primary neuron culture. …
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