Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 34 for “"rectal cancer"”.
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Living with locally advanced rectal cancer: an exploration of the everydayness of living with rectal cancer
… individuals are living with advanced cancer, yet services remain disease orientated. This thesis has documented the process of undertaking a longitudinal qualitative study to explore the everydayness of living with locally advanced rectal cancer. The study has identified how this can …
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Treatment Planning Automation For Rectal Cancer Radiotherapy
<h2>Background</h2> <p>Rectal cancer is a common type of cancer. There is an acute health disparity across the globe where a significant population of the world lack adequate access to radiotherapy treatments which is a part of the standard of care for rectal cancers. Safe radiotherapy treatments …
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Pre-surgical exercise intervention in prostate and rectal cancer survivors
… an introduction chapter of exercise and cancer, specifically prostate and rectal cancer (Chapter 1); two literature reviews, the first, a published systematic review examining the available literature on pre-surgical exercise in cancer and its effects on physiological and psychological …
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Sentinel Lymph Node in Rectal Cancer: Role of Transanal Endoscopic Microsurgery
L'abstract è presente nell'allegato / the abstract is in the attachment
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Risk Factors of Tumour Recurrence and Reduced Survival in Rectal Cancer
In Sweden, 2000 patients are diagnosed with rectal cancer annually. In 1995, the Swedish Rectal Cancer Registry (SRCR) was launched to supervise and assure the quality of the management of rectal cancer. Advances in the management of rectal cancer have reduced the local recurrence (LR) rate and …
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Immunocytochemistry Of Rectal Cancer Circumferential Margins In The Assessment Of Micrometastatic Disease
… peripheral circulation and bone marrow of colorectal cancer patients. Furthermore, micrometastatic disease has been shown to be associated with recurrence of the disease. However, there is no evidence of investigation into the micrometastastic disease at the circumferential margins of rectal …
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Use of Human Reliability Analysis to evaluate surgical technique for rectal cancer
… by different surgeons following surgery for rectal cancer. It is possible to improve such outcomes by focused training and the adoption of specific surgical techniques, such as the total mesorectal excision (TME) training programme in Stockholm which reduced local recurrence rates of cancer …
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Preoperative Chemoradiotherapy of Locally Advanced Rectal Cancer: Preliminary Results of BID Fractionation
… modality for patients with locally advanced rectal cancer. This study was designed to evaluate the efficacy, tolerance, and toxicity of preoperative chemoradiotherapy (CRT) using BID fractionation in patients with locally advanced rectal cancer. PATIENTS AND METHODS: Between January 2001 and …
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Expression of Survivin : Possible Predictor of Local Recurrence after Curative Resection for Rectal Cancer
… has always been a challenging problem following rectal cancer surgery, desite of the advances in surgical technique(TME) as well as adjuvant therapy(preoperative CCRT). There is a need for better prognostic markers due to the varieties of treatment response within same clinicopathologic stage. …
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Evaluating the functional effects, morbidity, recurrence, survival and quality of life after curative treatment for rectal cancer
Treatment for rectal cancer can be associated with rectal functional impairment, increased morbidity and may impact quality of life. Restorative surgery is the preferred choice of surgery, but in some circumstances, surgery with a permanent stoma is required to ensure tumour clearance. While the …
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Evaluation of the Survival Effect for Various Treatment Modalities Among Stage II and III Rectal Cancer Patients in California, 1994-2009
… receiving radical surgery for stage II and III rectal cancer (RC).</p> <p><strong>Patients and Methods</strong>: We conducted a nonconcurrent cohort study evaluating demographic predictors of multimodal therapy for stage II and III RC using the diverse California Cancer Registry population-based …
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Development and validation of risk prediction model for colorectal cancer in patients with gastrointestinal symptoms
BACKGROUND: Colorectal cancer (CRC) is a malignant tumour that grows in the colon and/or rectum. According to the global burden of disease estimate, in 2020, CRC was the third most common cancer and the second leading cause of cancer-related death in the world, with approximately 1.9 million CRC …
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Phenotypic dynamics of rectal cancer under neoadjuvant therapy: a multi-omic single-cell perspective from patient-derived organoids [Evoluzione fenotipica del carcinoma del retto durante terapia neoadiuvante: una prospettiva multi-omica a singola cellula da organoidi derivati dal paziente]
Questo studio esplora i meccanismi di adattamento fenotipico e l’eterogeneità intratumorale (ITH) nel carcinoma colorettale, con particolare attenzione alle forme localmente avanzate di carcinoma del retto. La resistenza terapeutica rappresenta una delle principali sfide in oncologia; comprenderne …
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Prognostic role of tumour associated trypsin inhibitor in colorectal cancer patients
Colorectal cancer (CRC) is one of the most common forms of human cancer worldwide with approximately 1 million new cases detected every year. CEA is currently the only accepted CRC marker incorporated into clinical practice, where it is used for early detection of metastasis in follow-up of …
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Proteomic identification of putative biomarkers of radiotherapy resistance
… derived from breast, head and neck (oral), and rectal cancers were investigated to identify differentially expressed proteins (DEPs) associated with radiotherapy resistance. This included the establishment of 2 RR rectal cancer cell line models and the proteomic analysis of 2 RR oral cancer cell …
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Elucidating the Multi-omics of Early-Onset Colorectal Cancer
… and mortality rates of sporadic early-onset colorectal cancer have increased in recent decades, but there is no clear etiological basis for this trend. EOCRC is commonly defined as colon and rectal cancers diagnosed before the age of 50 years. The rising incidence of EOCRC has made it the second …
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Atr-Mediated Cd47 and Pd-L1 Upregulation Restricts Radiotherapy-Induced Immune Priming and Abscopal Responses In Colorectal Cancer
<p>Radiotherapy of colorectal cancer (CRC) can prime adaptive immunity against tumor-associated antigen (TAA)-expressing CRC cells systemically. However, incidences of abscopal tumor remission are extremely rare, and the post-irradiation immune escape mechanisms in CRC remain elusive. We report …
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The role of biofeedback in improving anal continence after anterior resection
… biofeedback into the management of patients with rectal cancer who are undergoing anterior resection offers potential for improved anal continence compared with standard management. A multicentre randomised controlled trial was performed to investigate this and 121 participants undergoing major …
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The Relationship Between Uncertainty in Illness and Anxiety in Patients With Cancer
Anxiety is a common problem for patients with cancer. Anxiety may have a negative impact on decision making and overall emotional well being of patients and may be related to the uncertainties faced by people with cancer. This study examined the relationship between uncertainty in illness and …
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MODEL OF ESTIMATION OF LOCAL CONTROL AND SURVIVAL BENEFIT OF EXTERNAL BEAM RADIOTHERAPY FOR SELECTED CANCERS
… (OS) benefits of radiotherapy for selected cancers if the whole cancer population in Australia were treated according to evidence-based guidelines. These estimates were based on the published radiotherapy utilisation (RTU) models used for estimating demand of radiotherapy services nationally …
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