Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"receptor-histidine kinase"”.
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Targeting Receptor-Histidine Kinase Signaling in Staphylococcus Aureus
<p>Two-component signaling systems involving receptor-histidine kinases (RHKs) are present in all branches of life outside of the animal kingdom. Remarkably, very little is known concerning the extracellular ligands that presumably bind to RHKs to initiate signaling. The two-component agr signaling …
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Mechanism of Signal Transduction By The Staphylococcus Aureus Quorum Sensing Receptor AGRC
<p>Bacteria use receptor histidine kinases to sense extracellular cues and convert them into intracellular signaling events that allow them to respond to their environment. In Staphylococcus aureus, each individual cell must sense the size of its overall population in order to synchronize virulence …
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Studies on the Maturation of Secreted Quorum Sensing Peptides That Regulates S. Aureus Virulence
… of their concentration via AgrC, a transmembrane receptor histidine kinase, coordinates local bacterial population density with global changes in gene expression. In order for S. aureus to produce AIP, three proteolytic transformations involving the proteins AgrB and SpsB are required. However, …
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Reconstitution and Mechanistic Studies on the Staphylococcal agr Quorum Sensing Circuit
… The second study focused on the AIP-sensing receptor histidine kinase (HK), AgrC, whose auto-phosphorylation exhibits several remarkable properties in our reconstitution system based on nanometer-scale lipid-bilayer discs (nanodiscs). Activation of this receptor by its native activator, for …