Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"receptor oligomerization"”.
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Molecular Mechanisms of Serotonergic Signaling: Role in Neuronal Outgrowth and Receptor Oligomerization
Rolle des 5-HT7/G12 Signalwegs bei der Morpho- und Synaptogenese. Der Neurotransmitter Serotonin (5-Hydroxytryptamin oder 5-HT) moduliert, zusätzlich zu seiner Funktion als Neurotransmitter, verschiedene Aspekte der frühen neuronalen Differenzierung, einschließlich des Neuritenwachstums und der …
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QUANTITATIVE MODELING OF SCALING OF PATTERNS AND RECEPTOR SIGNALING IN MORPHOGENESIS
… mediated signal, were developed to analyze the receptor oligomerization that forms heterotetrameric receptor associations in BMP signaling. The oligomerization model disproves previous kinetic based hypotheses of heterodimer dominance, and identifies other theoretical conditions to acquire …
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Signal transduction via multiple BMP receptor complexes
… is transmitted via BMP type I and BMP type II receptors, both members of the serine/threonine kinase superfamily. The BMP receptor mediated signal transduction is not explored in detail. Therefore our aim was to address different aspects of BMP mediated signal transduction with main focus on …
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Investigating spatial distribution and dynamics of membrane proteins in polymer-tethered lipid bilayer systems using single molecule-sensitive imaging techniques
… Exemplary, dynamic processes of membrane protein oligomerization and distribution are of physiological and pathological importance. However, due to the complexity of the plasma membrane, the underlying regulatory mechanisms of membrane protein organization and distribution remain elusive. To …
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G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking
The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. Kinins are proinflammatory peptides that are rapidly produced …