Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 55 for “"rat-heart"”.
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MIBG uptake in the hypertensive-diabetic rat heart
… the integrity of the adrenergic nerve endings in heart and spleen was investigated. One week following streptozotocin (STZ) injection (55 mg/kg), male Sprague-Dawley rats were divided into two groups. They were given subcutaneous injections of either deoxycorticosterone-acetate (DOCA, 25 mg/kg) or …
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The Function Of Sarcoplasmic Reticulum In The Aged Rat Heart
… potential contribution to the age-related alterations in myocardial contractile performance in Fischer 344 rats.;In cardiac membranes enriched in SR (MSR) and its light (LSR) and heavy (HSR) subfractions fractionated by a sucrose density gradient, the rate of ATP-supported and …
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Chronic Hypoxia Induces Epigenetic Modifications in the Fetal Rat Heart
Heart disease remains the leading cause of death worldwide. As a result of studies done by Barker and associates, our awareness of the significance of stress during gestation as a risk factor for heart diseases has expanded. We now know that events in utero can significantly alter gene expression …
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Arrhythmogenic potential of alpha-adrenoceptor stimulation in the rat heart
… to ventricular fibrillation in the norrnoxic rat ventricular myocardium and further to evaluate the possible underlying cellular mechanism. The model used was the isolated perfused rat heart (Langendorff technique) in which ventricular fibrillation was electrically induced. The amount of …
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Computational biomechanics in the remodelling rat heart post myocardial infarction
… more than 33% of which are related to ischemic heart disease, including myocardial infarction (MI). This thesis seeks to provide insight and understanding of mechanisms during different stages of MI by utilizing finite element (FE) modelling. Three-dimensional biventricular rat heart geometries …
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Investigations into mechanisms of magnesium homeostasis in the isolated rat heart
… is essential for normal functioning of the heart. It is the second most abundant divalent cation in living cells and plays vital roles in cellular regulation. Preservation of intracellular Mg 24 concentration ([Mg24]) is essential in the heart. The concentration of ionized Mg 24 is similar …
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Effects of streptozotocin diabetes on the noradrenergic innervation of the rat heart
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Effects of Leonotis leonorus aqueous extract on the isolated perfused rat heart
… end-diastolic pressure, developed pressure, heart rate, cardiac work and coronary perfusion pressure in isolated rat hearts.
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Effect of halothane on carbohydrate and lipid metabolism in the rat heart
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Myocardial intermediary metabolism: with special reference to the isolated, contracting, perfused rat heart
… arterio-venous differences of various substrates, Sing and other workers (Goodale, Olson) have been able to describe the overall picture of myocardial metabollism in man and intact experimental animals. This technique dos not, however, allow adequate pinpointing of the precise pathways of …
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The effect of guanine nucleotides on glucagon-sensitive adenylate cyclase in the rat heart
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Molecular Characterization of the Regulatory Subunits of Voltage -Dependent Calcium Channels From Rat Heart
… The alpha1 subunit is essential for current generation, voltage sensing and drug interaction, whereas the regulatory subunits modulate channel properties including current amplitude, kinetics and voltage-dependence. To date, 10 alpha1, 4 alpha2delta, 4 beta, and 8 gamma genes have been …
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Cardiovascular effects of Leonotis leonurus extracts in normotensive rats and in isolated perfused rat heart
… tested on anaesthetized normotensive male Wistar rats and isolated perfused rat hearts.
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Preconditioning and augmented preconditioning via manipulation of metabolic and signalling pathways in the rat heart
… ischaemic stimulus confers protection to the heart against subsequent prolonged ischaemia and reperfusion injury. Understanding this survival programme will enable us to augment tissue tolerance against cell death. Ischaemic preconditioning is poorly understood, however, certain metabolic …
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