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Showing 1 to 12 of 12 for “"rat strain"”.

  1. Effect of Rat Strain Stereotactic Coordinates on Infarct Volume

    Sanghvi, Saagar K.Wright State University2013

    … treatment for these cases is intravenous administration of tPA within a 3.5 hour window from stroke onset. A long-term delayed ischemic stroke treatment proposed by this study was a combination of the pharmaceuticals Fluoxetine (SSRI), Simvastatin (statin), and ascorbic acid (Vitamin C). 51 adult …

    ohiolink Repository record

  2. The effects of rat strain, sex and THC on brain and behaviour : factors that alter the sensitivity to drugs of abuse

    Keeley, Robin J.2014

    lethbridge

  3. Network mechanisms underlying susceptibility to helplessness and response to the antidepressant fluoxetine

    Padilla, EimeiraUniversity of Texas at Austin2010

    … stress exposure using a stress-susceptible rat strain, 2) to identify the neural network effects of response and non-response to SSRI treatment using a stress-susceptible animal model, and 3) to determine the neurophysiologic correlates of helplessness susceptibility. This was examined via …

    texas Repository record

  4. FROM DISEASE TO THE GENE - Identification of arthritis-regulating loci in rats

    Rintisch, CarolaDepartment of Experimental Medical Science, Lund Univeristy2009

    … towards various arthritis models of two DA rat substrains. We detected several genetic and phenotypic differences, suggesting that one of the substrains had been genetically contaminated from another rat strain. The second study is based on the observation that a spontaneous mutation in our …

    lund Repository record

  5. Ubiquitin Conjugase UBE2K Is Essential for Normal Rat Development and Spermatogenesis

    Chaudhary, Jaideep2018

    … early 1980's [Reviewd by (Hamra, 2010)], the laboratory mouse has emerged as the most widely published animal model in science (NCBI, PubMed). Interestingly, prior to the year 2000, annual publications in the laboratory rat outnumbered annual publications in the mouse by greater than 2-3 fold in …

    utswmed Repository record

  6. Circulating sex hormone levels in rats: a systematic analysis of the literature and perinatal BPA study

    Meisner, Eleanor FrancesUniversity of Illinois at Urbana-Champaign2016

    … a systematic analysis of the available literature to characterize within the rat model how three different, popular outbred strains (Wistar, Sprague-Dawley, and Long-Evans) may each possess distinct levels of basal peripheral testosterone (T), estradiol (E2), or progesterone (P4) levels, …

    uiuc Repository record

  7. Modulation of the T cell response with MHC class I peptides and their analogues

    Sitaru, Ana GabrielaUniversität Würzburg

    … stages of organ failure. It has been demonstrated that transplantation between genetically non-identical individuals leads to the activation of the recipient’s alloimmune response as a major determinant of transplant outcome. T cell recognition of foreign MHC molecules plays a key role in …

    wurz-thes Repository record

  8. Physikalische Kartierung der RT1-C/M-Region des Haupthistokompatibilitätskomplexes der Ratte

    Ioannidu, Sofia2012

    The rat is an important model for studying organ graft rejection and susceptibility to certain complex diseases. The MHC, the RT1 complex, plays a decisive role in controlling these traits. During this work is cloned the telomeric class I region of the RT1 complex, RT1-C/E/M, of the BN inbred rat …

    goettingen Repository record

  9. Effects of Aerobic Capacity Phenotype on Adaptive Responses to Ischemic Stress

    Fontenot, Elizabeth GailEast Carolina University2009

    … of the vascular network to sustain substrate delivery and adaptive responses within affected tissue to sustain function despite diminished substrate availability. Active aerobic exercise has been shown to improve both vascular and metabolic remodeling within and around ischemic tissues. …

    ecu Repository record

  10. Aging and Sympathetic Neurotransmission in Two Strains of Rats that Differ in Longevity and Immune Profiles

    Perez, Sam David

    … established. From previous studies in Fischer rats (F344), we have found that during middle age, sympathetic nerve activity (SNA) rises in the spleen followed by a decline in noradrenergic (NA) innervation. Also, increased sympathetic signaling via betaadrenergic receptor (β-AR) and reduced …

    loma-linda Repository record

  11. Deciphering host-parasite molecular networks mediating resistance to toxoplasma gondii

    Kim, Chi YongUniversity of Illinois at Urbana-Champaign2018

    … and prophylactic agents against T. gondii. Rats, like immunocompetent humans, develop a chronic infection, but vary in their susceptibilities to T. gondii infection depending on the rat strain. Compared to the T. gondii-susceptible Brown Norway (BN) rat, the Lewis (LEW) rat is extremely …

    uiuc Repository record

  12. The role of norepinephrine in arousal and attention: a human and rat study

    Howells, Fleur MargaretDepartment of Human Biology2009

    … the LCNE system to enhance the signal-to-noise ratio in stimulus-related neural networks. In addition terminal release of NE from LC neurons responds synergistically with glutamate release from glutamatergic neurons, thereby potentiating its signal. The Yerkes and Dodson (1908) theory of arousal …

    cape-town Repository record