Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 170 for “"rat brain"”.
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Intracellular distribution of pentobarbital sodium in rat brain
"The major effect of the barbiturates is depression of the central nervous system, but the way in which these drugs exert their effect is not yet well understood...As the biochemical functions of the cell and its various parts become better understood, it is of interest to relate the actions of t a …
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Neuronal activity and membrane turnover in rat brain
… Institute of Technology, Dept. of Brain and Cognitive Sciences, 1993.
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Glycosaminoglycans and proteoglycans in the developing rat brain
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1996.
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Membrane mechanism of progesterone actions on the rat brain
… a variety of physiological functions in discrete brain areas of mammals. It is generally held that actions of stroids in the CNS are mediated via genomic mechanisms. However, there are at least three lines of evidence indicating that a nongenomic mechanism of P's action is also involved. First, P …
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Continuous low dose rate irradiation of the rat brain
… high grade astrocytomas and who undergo postoperative radiotherapy is of the order of 24 to 40 weeks. The course of radiotherapy administered to these patients takes up a considerable portion of their expected survival time. Therefore, any means of reducing the treatment time may contribute to …
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Interactions of acetylcholine and phospholipid metabolism in rat brain
… Institute of Technology, Dept. of Brain and Cognitive Sciences, 1994.
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Transcriptional Regulation of Matrix MetalloProteinase-3 in Rat Brain Astrocytes.
… regulation of MMPs. Here we demonstrated transcriptional regulations of MMP-3 in LPS-, IFN?^-, and gangliosides-activated cultured astrocytes obtained from rat brain. MMP-3 transcript and protein were increased by stimulation with LPS, IFN?^ and gangliosides. Promoter analysis …
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Anti-Inflammatory Mechanism By Oxysterols In Cultured Rat Brain Astrocytes
"Cholesterols are enriched in the brain and can be oxidized to oxysterols by spontaneous or enzyme-mediated processes. Oxysterols are transport forms of cholesterols across cell membranes and the blood-brain barrier. Here, to elucidate the roles of oxysterols in brain inflammation, I treated …
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Analysis of rat brain lipids and metabolites after antidepressant drug treatment
… paroxetine. The effects of the drugs in rat brain regions implicated in depression: the prefrontal cortex (PFC), hippocampus (HP) and striatum (ST) were investigated both acutely (single administration) and chronically (daily treatment for 15 days). In Chapter Three, ¹H NMR spectroscopy …
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Electrical Activity of Rat Brain as a Correlate of Primary Drive
Made available in DSpace on 2014-12-03T23:51:11Z (GMT). No. of bitstreams: 1 6004000.pdf: 3063524 bytes, checksum: af80cbb41c86f03f71ebd6805fefce4b (MD5) Previous issue date: 1960
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Release of Histone Lysine Methyltransferases from Rat Brain Chromatin by Nuclease Digestion
… (12-16%) of chromosomal DNA from rapidly proliferating rat brain chromatin with micrococcal nuclease. The enzymes were further purified by gel filtration, ammonium sulfate fractionation and DEAE-cellulose chromatography. The histone methyltransferases were resolved into two distinct fractions by …
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DNA Damage Response in Huntington’s Disease and Naked Mole Rat Brain Ageing
… the molecular mechanisms underlying healthy brain ageing in the exceptionally long-lived naked mole rat (NMR) and the role of the DNA damage response in the pathogenesis of Huntington's disease (HD). Multi-omic analyses of NMR brain ageing revealed a lack of a canonical ageing signature in …
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Effects of Ganglioside GM1 on MDMA-Induced Serotonergic Neurotoxicity in the Rat Brain
… cell death. The ganglioside GM 1 has demonstrated potential neurotrophic properties which may enhance the rate of recovery of the neurons from the MDMA-induced effects. To assess this GM1 effect, MDMA (20 mglkg x 4 days), GM1 (40 mgkg), MDMA and GM1 or saline was injected (i.p.) into male …
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Induction of oxidative stress in rat brain and rat astrocytes by acrylonitrile (ACN)
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Taurine's effect on cocaine reward and neurogenesis in the adolescent male rat brain.
… from childhood to adulthood including both maturation of the body and the brain. Neuroplastic changes result in dynamic organization of the brain during adolescence, leaving them vulnerable to development of mental illness and drug-seeking behavior. According to the United Nations Office on …
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