Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"range uncertainty"”.
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Incorporating range uncertainty into proton therapy treatment planning
… and neck. Protons, unlike X-rays, have a finite range highly dependent on the electron density of the material they are traversing, resulting in a steep dose gradient at the distal edge of the Bragg peak. These characteristics, together with advancements in computation and technology have led to …
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Dual Energy Computed to mography For Proton Therapy Treatment Planning
… the proton radiation therapy.</p> <p>One major uncertainty in a proton treatment is the range uncertainty related to the estimation of proton stopping power ratio (SPR) distribution inside a patient. The SPR distribution inside a patient is required to account for tissue heterogeneities when …
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Improvements In Robustness and Optimality of Intensity-Modulated Proton Therapy Plans For Lung Cancer Patients With 4-Dimensional Robust Optimization
… both respiratory motion as well as to setup and range uncertainties simultaneously.</p> <p>For full 4DRO, the effect of respiratory motion, characterized by different phases of 4D computed tomography (CT), was incorporated into a 4DRO algorithm. Dose distributions from multiple setup and range …
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Range Adaptive Proton Therapy For Prostate Cancer
… structures are avoided due to concerns of range uncertainties, such as CT number conversion and anatomy variations. We propose to eliminate range uncertainty and enable prostate treatment with a single anterior beam by detecting the proton’s range at the prostate-rectal interface and …
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Intensity Modulated Proton Therapy Optimization Under Uncertainty: Field Misalignment and Internal Organ Motion
… to different uncertainties, such as setup uncertainty, range uncertainty and internal organ motion. These uncertainties can greatly impact the quality of clinical treatment. Therefore, this dissertation aims to investigate different optimization methods for treatment planning and to handle …
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Evaluation and Clinical Implementation of a Dual-Energy CT Stopping-Power Ratio Mapping Technique for Proton-Therapy Treatment Planning
… rapid dose falloff at the end of the proton-beam range is correctly aligned to the edge of the clinical target volume (CTV). However, its clinical potential is dependent on the accurate localization of the Bragg-peak position from predicted stopping-power ratio maps. The method that is most …
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Implications of uncertain future network performance on satisfying environmental justice and tolling
… methods for exploring the pressing problems of uncertainty, Environmental Justice, and tolling as they relate to long-range transportation planning. While these topics are seemingly disparate, much of the work in this dissertation is motivated by the increasing number of roadway projects …
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A new prompt gamma spectroscopy-based approach for range verification in proton therapy
… in a localized region close to the end of their range (called the Bragg Peak BP). The combination of the favorable depth-dose profile with advanced delivery techniques translates into a high dose conformality in the tumor, as well as into a superior sparing of normal tissue compared to …