Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 120 for “"randomised controlled trials"”.
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Recruitment to randomised controlled trials with children
Recruitment to randomised controlled trials is known to be difficult. Poor recruitment has several adverse consequences. It affects the validity of study findings, is a common cause of trial extensions and may result in premature termination of trials, which is a huge loss in terms of invested …
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Detection of safety signals in randomised controlled trials
… adverse events are routinely recorded during randomised clinical trials. This data is used by a trial's Data Monitoring Committee to make decisions regarding the safety of a treatment and may lead to the alteration or discontinuation of a trial if real safety issues are detected. There are …
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Bayesian Methods for the Design and Analysis of Cluster Randomised Controlled Trials
Cluster Randomised Controlled Trials involve randomising groups of participants, rather than the individual participants themselves, whilst the outcomes are measured on the participants. Whilst there are a number of practical and methodological advantages to such a design, there are also …
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Overcoming Challenges in Randomised Controlled Trials and Systematic Reviews in Periodontal Research
… and overcomes challenges experienced in randomised controlled trials and systematic reviews in periodontal research. The narrative review provides an overview of the current understanding of the aetiopathogenesis and epidemiology of periodontal disease as well as a description of the …
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Mapping perioperative randomised controlled trials in Sub-Saharan Africa: a scoping review
… period. SSA conducts fewer randomized controlled trials (RCTs) than high-income countries, limiting its contribution to global evidence. Objectives: Our primary objectives were to document the geographical distribution of included RCTs, describe their characteristics, and evaluate the …
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RANDOMISED CONTROLLED TRIALS ON PSYCHOLOGICAL INTERVENTIONS TO PROMOTE MENTAL HEALTH OF COMMUNITY-DWELLING ELDERLY
… prompted us to initiate two randomized-controlled trials. Methods: Systematic review and meta-analysis were employed to examine aggregate serum BDNF levels. Subsequently, to examine the effects of the interventions, biomarkers candidates and psychometric measures were utilised. Results: …
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The conduct of randomised controlled trials in China: quality of trial reports and stakeholders’ views
China is an emerging force in undertaking randomised clinical trials. The quality of trials from China may affect not only its own substantial population but also potentially contribute to health policy throughout the world. However, little is known about the quality of clinical trials conducted …
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Alcohol Intervention Studies in University Students. Randomised Controlled Trials of Responsible Beverage Service and High Risk Drinking.
… a mailed personalised drinking feedback. We used randomised controlled trials to examine the efficacy of the interventions. In order to study the influence of a respo-nsible beverage service, a training programme were given to bartenders at local student pubs (N=12) in a random way. Bartenders at …
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Nutrition counseling in adults infected with the Human Immunodeficiency Virus : a systematic review of randomised controlled trials
… databases and conference proceedings for all randomised controlled trials (RCTs) of nutrition counselling compared with either no nutrition counselling, oral supplements, or with nutrition counselling plus oral supplements. Two reviewers independently assessed the eligibility of the studies …
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The prognostic value of HIV viral load in predicting viraemic outcomes of post-partum women on antiretroviral therapy: a secondary analysis of two randomised controlled trials from Gugulethu, Cape Town
… of transient viraemia, even in previously well-controlled individuals on ART, are not fully understood and may contribute to ongoing mother-to-child transmission (MTCT) despite therapy that is otherwise optimal. Methodology: Two randomised controlled trials (RCTs), the MCH-ART and PACART trials, …
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Learning to Field Test in Policing: Using an analysis of completed randomised controlled trials involving the police to develop a grounded theory on the factors contributing to high levels of treatment integrity in Police Field Experiments.
… most contentious areas is the role advocated for randomised controlled trials in testing practice and developing knowledge to support EBP. RCTs are controversial with some scholars who argue that policing is not comparable to medicine and that RCTs are unable to reflect the complexity of the …
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Early mobilisation after coronary angiography to reduce back pain
… which included fifteen studies; eleven randomised, two quasi-randomised and two non-randomised controlled trials. The studies were collated, evaluated and summarised using the Cochrane Collaboration’s framework. Each individual study was also graded for quality of the evidence by …
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The human rights implications of adopting male circumcision as a prevention stratergy for HIV/AIDS in South Africa
… in South Africa. Consistent findings from three randomised controlled trials in sub-Saharan Africa reflect a protective effect of male circumcision on HIV infection. Given the attention bestowed on the topic by popular media and the international HIV / AIDS community alike, it is justifiable for …
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Substance abuse programs that reduce violence in a youth population : systematic review
… heterogeneity of outcomes and the paucity of randomised controlled trials (RCTs). Abstracts were screened by two reviewers, as were selected full texts articles. These were evaluated using the EPHPP questionnaire, a quantitative study assessment tool to identify methodological issues.
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The use of assisted autogenic drainage in children with acute and chronic respiratory disease
… review, two systematic reviews and two pragmatic randomised controlled trials.
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The prevention of adverse neurodevelopmental outcomes in children born to diabetic mothers
… incidence of GDM. In particular, there were no trials of interventions before or between pregnancies to reduce the risk of GDM. The prospective follow-up of children from two randomised controlled trials of prophylactic oral dextrose gel to prevent neonatal hypoglycaemia, one of different doses …
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Herbal medicines:physician's recommendation and clinical evaluation of St.John's Wort for depression
… evaluated herbal remedy with no fewer than 57 randomised controlled trials. Evidence from the depression trials suggests that St. John's wort is more effective than placebo while its comparative efficacy to conventional antidepressants is not well established. We updated previous meta-analyses …
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Klinische impact en medische veiligheid van digitale ondersteuning (EXPERT tool) in selectie van oefenmodaliteiten tijdens cardiovasculaire revalidatie
… Op PubMed en Web of Science werd er gezocht naar randomised controlled trials en systematic reviews over telemonitoring en digitale ondersteuning in het voorschrijven van trainingsmodaliteiten bij patiënten met hartfalen of coronaire vaataandoeningen. De studies werden door twee onderzoekers …
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Rapid versus slow rate advancement of feeds for enterally fed extremely low birth weight infants < 1000g: randomised controlled trial
… enterocolitis (NEC). Objective 1. To review randomised controlled trials (RCT); examining the effect that the rate of advancement of enteral feeds has on the incidence of; NEC, mortality, growth, health care utilisation and other morbidities in very low birth weight (VLBW) and extremely low …
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