Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"random peptide library"”.
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Construction and mutagenesis of an anti-insulin single chain Fv (scFv) using protein engineering techniques: Identification of peptide mimotopes which inhibit scFv-insulin binding.
Peptide mimotopes were found using random peptide library technology (Selectide technology) which bind to the paratope of an anti-insulin monoclonal antibody. These peptides inhibit insulin from binding to the anti-insulin antibody, indicating that they share at least part of the paratope for …
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Heterotrimeric G protein beta:gamma bound to a biologically active peptide : structural definition of a preferred protein interaction surface
… The 2.7Å crystal structure of Gβ1γ2 bound to a peptide (SIGKAFKILGYPDYD) obtained from a random peptide library has been solved. This peptide inhibits Gβγ mediated activation of phospholipase C β and phosphatidylinositol-3-kinase γ and binds Gβ with sub-micromolar IC50. Gβ is a seven-stranded …
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Identification of MRSA-specific peptides and expression of peptide containing recombinant proteins for targeted photodynamic therapy
… treatment.The FliTrx (TM) bacterially-displayed random peptide library (Invitrogen), displaying 12-mer peptides in a conformationally constrained manner on the surface of E. coli was screened by panning against UV-inactivated MRSA. Panning was also performed against S. aureus and S. epidermidis …
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Design, Herstellungsoptimierung, Charakterisierung und Anwendung einer randomisierten, auf Adeno-assoziierten Viren exprimierten Peptidbank
… Viren (AAV), die an der Oberfläche randomisierte Peptidliganden exprimieren, welche ein Umlenken der Vektoren von ihrem natürlichen auf einen alternativen Rezeptor ermöglichen. Die Peptidliganden werden in der Region des Capsidproteins exprimiert, die an der Bindung von Wildtyp-AAV …