Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"rana box"”.
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Discovery and functional study of the novel bioactive peptide QUB-1980 from the skin secretion of Odorrana grahami
… the parent peptide to study the significance of “Rana box” in the novel peptide QUB-1980. Besides, it also exhibited a mild toxicity to horse red blood cell. Besides, by substituting the “Rana box” with a C-terminal amide, a shorter AMP, QUB-1347NH2, was designed based on the natural peptide. As a …
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Discovery, structural characterisation and targeted engineering of bioactive peptides from amphibian skin secretion
… side effects and reveal the function of the ‘Rana Box’ domain of QUB-3307, two truncated analogues, QUB-2531 and QUB-1376, were designed. QUB-2531 produced a low degree of cytotoxicity and haemolysis without decreasing the antimicrobial effect dramatically. However, QUB-1376 demonstrated lower …
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Discovery and design of novel bioactive peptides from the skin secretion of Ranidae frogs
… segment and a typical heptapeptide loop - the rana box. In Chapter 4, three novel peptides with highly-conserved primary structures were found in three different species of frog: the Green Mountain Frog (Odorrana livida), the Wuyi Torrent Frog (Amolops wuyiensis) and Schmacker’s Frog (Odorrana …