Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 65 for “"radiotracer"”.
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ABSOLUTE QUANTIFICATION IN SMALL PLANT RADIOTRACER STUDIES
… tools for improving the quantitative accuracy of radiotracer studies of small plants, e.g., grasses in their early growth stages and tree seedlings. Improved accuracy is needed due to the thin nature of plant organs, e.g., leafs and stem. In addition, the methods developed in this thesis are …
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Adsorption on smooth electrodes: A radiotracer study
… processes at smooth electrodes. The in situ radiotracer method is highly anion (molecule) specific and provides information on the structure and composition of the electric double layer. The emphasis of this research was on studying adsorption processes at smooth electrodes of copper, gold, …
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Surface Studies in Ultrahigh Vacuum by Radiotracer Techniques
Made available in DSpace on 2015-05-12T17:12:22Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 6101614.PDF: 2567226 bytes, checksum: 4e0acb26576b35847fc12380740caa9b (MD5) Previous issue date: 1961
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A radiotracer technique for in situ adsorbate measurements on smooth electrode surfaces
A prototype radiotracer apparatus for measuring in situ adsorption onto smooth metal electrodes has been developed. In this method, a radiolabeled adsorbate on an electrode is detected by pressing the electrode against a glass scintillator detector at the bottom of an electrochemical cell. …
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Microfluidic modules for pre-concentration of [¹⁸F]fluoride in positron emission tomography (PET) radiotracer synthesis
… been explored as a promising alternative for radiotracer synthesis due to benefits such as (i) superior control over reaction conditions leading to high yields and conversion rates, (ii) reduced reagent consumption and radioactive waste production as well as (iii) potential for automation with …
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Anatomically aware machine learning modeling of PET count rates for detection and quantification of radiotracer extravasation
Υπόβαθρο: Η Τομογραφία Εκπομπής Ποζιτρονίων σε συνδυασμό με την Αξονι κή Τομογραφία (PET/CT) χρησιμοποιείται ευρέως για την εκτίμηση της έκτασης των νοσημάτων και της μεταβολικής δραστηριότητας. Ενώ η αξονική τομογραφία παρέχει ανατομική πληροφορία, η PET επιτρέπει την ποσοτική αξιολόγηση …
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Developing a selective sphingosine-1-phosphate-5 (s1p5) radiotracer to image oligodendrocytes using preclinical positron emission tomography (PET)
… and selectivity for their target. An agonist radiotracer would be of particular interest as S1P5 is a G-protein coupled receptor and agonists show a bias to binding receptors in the active state. If successfully translated, these ligands could aid in improving trials of novel therapeutics, …
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Onderzoek naar het werkingsmechanisme van acamprosaat, een geneesmiddel tegen alcoholverslaving, met behulp van een radiotracer voor positron emissie tomografie
… syntheseweg uitgedacht voor de productie van de radiotracer. De PET-radionuclide 11C werd geproduceerd via cyclotronbestraling. Daarna werd de radionuclide m.b.v. een computergestuurde syntheseopstelling in de acamprosaatmolecule ingebouwd. Tenslotte werd het product chromatografisch opgezuiverd …
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Nitrate carrier induction and characterization in maize root plasma membrane using chlorate-36 as a radiotracer analog for nitrate
Previous studies with intact maize plants have shown an apparent induction of nitrate uptake capacity when plants are transferred to a nitrate containing nutrient solution. Whether this phenomenon reflects a change in nitrate carrier activity at the membrane level or an effect of nitrate metabolism …
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PET-imaging in depression and antidepressant therapies : focus on the serotonin system and the cerebral glucose metabolism
… several studies were performed using the PET radiotracer [11C]DASB, which specifically targets the serotonin transporter. To allow qualitative and safe research with this radiotracer, the first research topic focussed on the optimization of the radiotracer’s purification procedure and its …
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The development of a simple process for producing medicinal diagnostic 18F agents for molecular imaging using positron-emission-tomography
… approach for the synthesis of [18F]-fluoride radiotracers for use as imaging agents in positron-emission-tomography (PET). The RLV strategy immobilises a precursor to the desired radiotracer on a solid support which is cleaved on exposure to [18F]-fluoride ion to give the 18F-labelled …
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Développement d’une méthode d’immuno-imagerie permettant d’évaluer le statut immunitaire des tumeurs
… through the development and validation of a new radiotracer, 89Zr-4HMSA-anti-CD3. The method will be used to track tumor-infiltrating lymphocytes and thus assess the immunogenicity of the tumor. Our data show that the synthesis steps were efficiently carried out and that the product demonstrated …
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Development of a System for Real-Time Measurements of Metabolite Transport in Plants Using Short-Lived Positron-Emitting Radiotracers
… environment. Short-lived positron-emitting radiotracer techniques provide time-dependent data that are critical for developing models of metabolite transport and resource distribution in plants and their microenvironments. To better understand the effects of environmental changes on resource …
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Assessment of New Innovations In Pet/Ct For Respiratory Motion Correction
… abdomen. This leads to reductions in measured radiotracer concentration and lesion detectability all of which can potentially result in incorrect management of patients. Multiple methods exist to correct for respiratory motion but are rarely used in the routine clinical setting because of: 1) …
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MEASUREMENT AND MODELLING OF ESTUARINE CHEMISTRY
… Kd(Cd) and K<i(Zn) has been investigated using radiotracer incubation experiments and analytically determined measurements. The results show a reduction in IQ with increased salinity, but that the K<iS determined analytically are an order of magnitude higher than those measured when radiotracers …
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Radiotracers and NMR as in situ probes at the electrochemical interface
The design and construction of a radiotracer instrument which allows the quantitative measurement of a radiolabeled adsorbate on atomically smooth electrodes for the first time is described. Using this instrument, the surface mobilities of three organic molecules (pyridine, formic acid, and acetic …
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Synthesis of fluorinated cannabinoid derivatives; Towards PET radiotracers for imaging the cannabinoid receptor
… of the radiolabeled THC analog shows that this radiotracer readily entered the brain within 1-minute post-injection and was slowly cleared from the brain. To demonstrate specific binding of the radiolabeled cannabinoids to CB1R, control mice were injected with the CB1R antagonist rimonabant (1 …
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Silver Diffusion and Isotope Effect in Silver-Rubidium-Iodide
… been measured in both superionic phases using radiotracer Ag-110m and serial sectioning with a low temperature sectioning apparatus. The activation energies for diffusion in alpha-RbAg(,4)I(,5) and beta-RbAg(,4)I(,5), respectively, are .11 (+OR-) .01 eV and .20 (+OR-) .04 eV. These values are …
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Development of Novel PET Radiotracers for Neuroinflammation and COVID-19: Targeting FPR2, I2BS and ACE2
… that applies highly selective and sensitive radiotracers to biological markers. Imaging with PET radiotracers is a powerful means for the assessment and early detection of various diseases such as neurological diseases, cardiovascular diseases and cancer. Neuroinflammation is an inflammatory …
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