Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"radioprotection"”.
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Soy Isoflavones Mediate Radioprotection Of Normal Lung Tissue By Modulating The Radiation-Induced Inflammatory Response
… damage in the tumor. However, mechanisms of radioprotection by soy isoflavones in normal tissues remained to be elucidated. We hypothesized that soy isoflavones mediate radioprotection via the modulation of radiation-induced inflammatory processes involving macrophages, neutrophils, and …
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The Role of The Hypoxia-Inducible Factor 2 In Pancreatic Cancer: Mechanisms of Tumor Immunosuppression and Intestinal Radioprotection
… that Wnt5a is necessary and sufficient for SI radioprotection. Together, our results suggest that HIF2 radioprotects the SI, at least in part, by inducing Wnt5a expression.</p>
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Use Of Cerium Oxide Nanoparticles For Protection Against Radiation-induced Cell Death
… engineered cerium oxide nanoparticles to confer radioprotection was examined. Rat astrocytes were treated with cerium oxide nanoparticles to a final concentration of 10 nanomolar, irradiated with a single 10 Gy dose of ionizing radiation and cell death was evaluated by propidium iodine uptake at …
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Molecular Mechanisms of DNA Protection by Tardigrade Damage Suppressor Protein (Dsup): Structural Adaptation and Functional Interactions
… Dsup and its role in genomic protection. Beyond radioprotection, this work highlights the potential vi </p> <p>synergy between Dsup and tardigrade-derived Cytoplasmic Abundant Heat Soluble (CAHS) proteins, which stabilize cellular components under desiccation and thermal stress. Combining Dsup’s …
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ARTIFICIAL INTELLIGENCE AVAILABLE TO THE DEVELOPMENT OF A VIRTUAL REALITY SOFTWARE FOR AN AUTOMATED CEPHALOMETRIC ANALYSIS OF ULTRA-REDUCED CBCT FOV
… such as enhancing diagnostic precision, ensuring radioprotection, and optimizing clinical workflows through innovative technological solutions. Cephalometric analysis, a cornerstone of orthodontic diagnosis and treatment planning, has traditionally relied on manual or semi-automated methods using …
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Optimization of a GEM-based detector to measure tritium and discriminate against other radiation types
Tritium poses a radioprotection issue, in the Canadian Nuclear industry due to the operation of its fleet of Canadian Deuterium Uranium (CANDU) heavy water reactors. Although it is a less penetrative radionuclide, tritium is shown to have a detrimental effect on the human body when ingested, …
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United States and France : a regulatory perspective
… Generale de la Surete Nucleaire et de la Radioprotection (DGSNR) and the Electricite de France (EDF) control the nuclear industry, with the DGSNR controlling most of the regulation and the EDF presiding over the construction. In this thesis, the two systems of regulation will be reviewed …
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VIABILITY OF CERIUM OXIDE NANOPARTICLES AS A RADIOPROTECTOR AGAINST PROTON RADIATION FOR NON-MALIGNANT CELLS
… assay. While showing promise for potential radioprotection of non-malignant cells using both assays, the MTT assay results were less conclusive and require further research. The TUNEL assay results are preliminary but show that CNPs reduce DNA damage to non-malignant cells compared to those …
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Increased biopolymer pigment production in bacteria and fungi exposed to ionizing radiation
… the application of pigments for biocompatible radioprotection. These pigments' properties--including both UV and ionizing radiation absorption--lend themselves to interesting potential applications in biomedicine and biotechnology¹,². Some bacteria and fungi respond to ionizing radiation with …
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Fasting Reduces Intestinal Radiotoxicity Enabling Dose-Escalated Radiotherapy For Pancreatic Cancer
… orthotopic tumors. RT with fasting-mediated radioprotection delayed tumor growth and improved survival compared to controls. Given this robust phenotype, we developed a 3D culture ex vivo assay using intestinal stem cell-enriched epithelial spheroid cultures. We modified these intestinal …
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Bioengineering-enhanced neurosurgical solutions
… supporting the anticipated benefits in terms of radioprotection, and avoidance of post-radiosurgical deficits. Finally the neurotrauma section presents the clinical results from a prospective study on an innovative device for non-invasive monitoring of intracranial pressure, a tool that given the …
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EXPLORING THE PRE-LEUKEMIC PHASE OF ACUTE PROMYELOCYTIC LEUKEMIA: INSIGHTS FROM STUDIES OF SINGLE CELL ¿OMICS¿
… lethal irradiation, these cells provide radioprotection and long-term repopulation in recipient mice, indicating that PML-RAR confers an advantage that becomes particularly evident in perturbed conditions. Comparison with published datasets further reinforced our observations. A …
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AI Assisted Cellular and 3D Spheroid Analyses for Combined Therapies Against Glioblastoma
… cophenetic 0.866), showing lenalidomide provides radioprotection: radiation alone caused 80% cell death versus 40% for the combination, with 60% in an intermediate damaged state. This demonstrated that multi-modal imaging at multiple timepoints is essential for 3D models. For TMZ+GQD, machine …
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Etude des échantillons environnementaux par Spectrométrie gamma : cas des sols des campus I et II de l’Université de Douala
… qui ont été transmis à l’agence nationale de radioprotection.
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Nanoparticles For Biomedical Applications
<p>This thesis presents development and evaluation of the potential of three new nanoparticles for biomedical applications. With the rapid growth of the field of nanoscience, researchers have explored developing nanoparticles for various biomedical applications, including imaging, therapy, and drug …
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Screening of radioprotective agents using zebrafish and Therapeutic effects and protective mechanism of radioprotective candidates on radiation-induced oral mucositis
Screening of radioprotective agents using zebrafish and Therapeutic effects and protective mechanism of radioprotective candidates on radiation-induced oral mucositis Radiation-induced oral mucositis is a dose-limiting toxic side effect for patients with head and neck cancer. About 50–90% of cancer …