Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"radiation toxicity"”.
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Pharmacological countermeasures for the prevention and treatment of toxic radiation exposure in space flight
Ionizing radiation toxicity in space poses a significant occupational risk to astronauts and is an area of critical concern for space traveling agencies. However, despite technological advances in other areas, a viable solution to this problem has not been developed. The focus of this capstone is …
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Advancing Radiotherapy Treatment Through Artificial Intelligence-Driven Approaches
… Modern radiotherapy aims to deliver precise radiation doses to specific tumor target volumes while minimizing exposure to surrounding healthy tissues and organs. To achieve precision and high treatment quality, accurate target delineation, streamlined workflows, and timely follow-up are …
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Advancement of 31P Magnetic Resonance Spectroscopy Using GRAPPA Reconstruction on a 3D Volume
… monitoring and predicting treatment response to radiation therapy in liver cancer. Liver metabolism correlates with inflammatory and neoplastic liver diseases, which alter the intracellular concentration of phosphorus- 31 (31P) metabolites [1]. It is assumed that such metabolic changes occur …
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Can Intensity-Modulated Radiotherapy (IMRT) Be Used To Reduce Toxicity And Improve Tumour Control In Patients With Head And Neck Cancer?
… radiotherapy (IMRT) is a new form of focussed radiation therapy. It has been used to reduce the radiation dose to normal tissue structures and increase the dose delivered to tumour bearing tissues. This potentially allows reduced side effects and increased tumour control compared to …
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Prophylactic Cranial Irradiation Reduces The Incidence of Brain Metastasis In A Mouse Model of Metastatic Breast Cancer
<p>Prophylactic cranial irradiation (PCI) is a preventative whole-brain irradiation technique used to reduce the incidence of brain metastasis and improve overall survival in select patients with small cell lung cancer and acute lymphoblastic leukemia. A population of breast cancer patients – stage …
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Investigation of Radiation Injury In The Esophagus From Definitive Chemoradiation Therapy Using Novel Imaging Biomarkers
<p>Radiation injury in the esophagus occurs with high frequency from the treatment of non-small cell lung cancer (NSCLC). Radiation esophagitis is an acute normal tissue toxicity that negatively affects treatment efficacy by limiting dose and potentially interrupting radiation therapy. Clinical …
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The Combined Effect of In-Situ Tumor and Irradiation on Peritumoral Brain Vasculature
… surgical resection, when possible, followed by radiation therapy (RT) and/or chemotherapy. Radiation therapy is one of the most effective treatments of brain tumors; however, the therapeutic ratio of RT is limited by damage to the normal tissue. We hypothesize that tumor growth has an adverse …