Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"radial arm maze"”.
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Comparing the Effects of Various Estrogen Replacement Paradigms on Working Memory Performance in the Radial-Arm Maze
… animals were tested over 24 days in the 8-arm radial maze. After this acquisition period, various delay times were introduced between 4th and 5th arm choices. Treatments had no effects during acquisition or delay trials of 1 min, 10 min, and 3 hours. However, when a 5-hour delay was …
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Selective memory impairments produced by transient lidocaine-induced lesions of the nucleus accumbens
… remains unclear. The delayed spatial win-shift radial arm maze task has been used as a selective behavioral measure of damage to the hippocampal system, whereas the cued win-stay version of this task is unaffected by hippocampal lesions, but is disrupted by lesions in the dorsal striatum. The …
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Effects of bisphenol A exposure during early development on behavior and anatomy of the prefrontal cortex in adult male and female rats
… female from each litter were trained on the 17-arm radial arm maze in adulthood. Several weeks following completion of training, brains were removed from these rats to stereologically assess neuron and glia number in the medial prefrontal cortex. Results indicated that levels of T4 at weaning …
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Effects of perinatal dietary choline supplementation on learning and memory in the adult rat
… reference memory (visual discrimination t-maze), nonspatial working memory (delayed nonmatching-to-sample), and spatial working and reference memory (17-arm radial arm maze). Testing began when all subjects had reached at least 70 days of age. Significant differences were found on all tasks …
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Effect of Epigallocatechin-3-gallate on a pattern separation task and hippocampal neurogenesis in a mouse model of Down syndrome
… dose did not rescue deficits in the Morris water maze spatial learning task (MWM) or novel object recognition (NOR). Others have reported that An EGCG dose of 2-3 mg per day (90mg/ml) improved hippocampal-dependent task deficits in Ts65Dn mice. The current study investigated deficits in a radial …
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Impact of Corticosterone and Zinc Deprivation on Memory and Hippocampal Functioning
… the animals treated with CC. Performance on the radial arm maze was significantly correlated with the width of the CA3 pyramidal cell layer. Performance on the water maze was significantly correlated with the concentration of zinc in the vesicles in the CA1 and CA3 areas of the hippocampus.</p>
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Characterising hippocampal replay in the APP<sup>NL-G-F</sup> mouse model of Alzheimer’s disease
… region of the hippocampus as mice performed a radial-arm maze task, and during subsequent sleep. The task was designed to separably identify errors in reference and working memory. APP<sup>NL-G-F</sup> mice were found to make greater numbers of reference memory errors than control animals. This …
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Behavioural, genetic and epigenetic determinants of white matter pathology in a new mouse model of chronic cerebral hypoperfusion
… and long term memory recall were taxed using radial arm maze and water maze paradigms one month after surgery. At the completion of the behavioural testing white and grey matter integrity, inflammation were evaluated using standard immunohistochemistry with antibodies recognizing neuronal …
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A role for the SHANK1 scaffold protein in experience-induced synaptic plasticity and memory consolidation
… impairments in contextual fear-conditioning and radial-arm-maze retention. Similarly, mice that overexpress SHANK1 exhibit impairments in both cued and contextual fear conditioning, further suggesting that appropriate SHANK1 regulation is crucial for normal cognition.Collectively, these studies …