Global ETD Search
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Showing 1 to 2 of 2 for “"rac1 GTP-Binding Protein"”.
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Hyperactive Rac1 Drives MAPK-Independent Proliferation in Melanoma by Assembly of a Mechanosensitive Dendritic Actin Network
… describe how a hyperactivating mutation of the Rac1 GTPase (Rac1P29S) harnesses Rac1's function as a regulator of actin polymer assembly to sustain cell cycle progression in growth limiting conditions. This proliferative advantage supports metastatic colonization of melanoma cells and confers …
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Regulation of p190RhoGEF by Activated Rho and Rac GTPases: Amplification and Crosstalk
The Rho family of monomeric GTPases regulates a wide range of cellular processes including cytoskeletal structure, motility, cell division, gene transcription, vesicular transport, and various enzymatic activities. Activation of Rho proteins largely depends on Rho Guanine nucleotide Exchange …