Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"rRNA biogenesis"”.
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Characterization of a novel family of nucleolus localized RNAs
… domain where ribosomal gene transcription, pre-rRNA processing, and the initial steps of ribosome sub-unit assembly take place. In human cells, nucleoli are formed around nucleolar organizer regions (NORs) located on the short arms of the five acrocentric chromosomes. NORs are composed of tandem …
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Histone Post-translational Modification Dysregulation Contributes to Toxicity in Amyotrophic Lateral Sclerosis Proteinopathy Models
… Nop1, a histone methyltransferase involved in rRNA biogenesis, is a binding partner of FUS. We propose that exclusion of Ipl1 from the nucleus is driving the dysregulation of histone PTMs and that reduced levels of H3K56ac and FUS-Nop1 binding are causing reduced total RNA levels, likely …