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Showing 1 to 20 of 208 for “"quorum sensing"”.
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Mathematical Models of Quorum Sensing
… We present mathematical models dealing with quorum sensing, which is the biological process of communication in bacteria. The density-dependent means of communication are mediated by molecules called autoinducers that are both synthesized and collected by quorum sensing bacteria. We employ …
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Investigation of quorum sensing process in Bacillus licheniformis
Quorum sensing is a well-established system of communication adopted by a number of bacterial, and some fungal, populations. This cell density dependent phenomenon is based on the accumulation of small diffusible molecules, termed as quorum sensing molecules, in the extracellular milieu until a …
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Synthesis and evaluation of novel quorum sensing inhibitors
… furanones and the subsequent evaluation of their quorum sensing inhibitory effects. Chapter One focuses on the role of quorum sensing in bacteria and fungi. It explores the potential use of quorum sensing inhibitors as an alternative to, or in combination with antibiotics during the treatment of …
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Genetic Analysis of the Quorum Sensing Regulator EsaR
… production of EPS is regulated by an EsaI/EsaR quorum sensing mechanism, homologous to the LuxI/R system. Although activation of the EPS encoding genes by EsaR occurs after it complexes to the AHL (3-oxo-C6-HSL), unlike the LuxI/R system, this activation occurs by a different mechanism. At low …
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Identification of Quorum Sensing Genes in Hypersaline Microbial Mats
… conditions. One such pathway is called quorum sensing (QS), a cell-density dependent phenomenon involving the production, release, and detection of small diffusible signaling molecules referred to as autoinducers. This pathway ultimately coordinates gene expression among the bacterial …
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Dynamic Regulation of Metabolic Flux Using Orthogonal Quorum Sensing
… chemicals. One dynamic regulation strategy is quorum sensing (QS), a cell-to-cell communication that allows populations of cells to function as a collective. By applying QS to engineered pathways, the diversion of metabolic resources can be coupled to the population of the culture, thereby …
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Engineering LuxR-type quorum sensing proteins for new functions
… communicate information in a process known as quorum sensing, actuating downstream gene expression based on cell-cell signalling. Cell-cell signalling allows for complex and multi-cellular behavior otherwise impossible with unicellular logic. However, building complex cell-cell signalling …
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Studying the Competence Regulon Quorum Sensing Circuity in Streptococcus mitis
Quorum sensing (QS) is a bacterial mechanism for modulating gene expression in response to cell-population density via intercellular communication. QS bacteria generate and release chemical signal molecules known as autoinducers, which increase in concentration as cell density increases. To …
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Quorum Sensing and Virulence Regulation in Commensal and Pathogenic Bacteria
Quorum sensing (QS) is a peptide-mediated bacterial communication process that regulates collective behaviors including genetic competence, biofilm formation, virulence, and horizontal gene transfer. In streptococci, QS commonly occurs through the ComABCDE and ComRS signaling pathways, which …
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The Effects of Quorum Sensing Molecules on Streptococcus mutans Biofilm
The use of quorum quenching (QQ) molecules to prevent biofilm formation has recently gained momentum. Interrupting the quorum sensing (QS) pathways of cariogenic bacteria like Streptococcus mutans could reduce the formation of dental plaque on teeth, lowering the incidences of caries and …
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Estudio de protocolos de comunicación bacterianos: conjugación y quorum sensing.
… las bacterias son la detección de quórum o quorum sensing y la conjugación. El quorum sensing es un mecanismo que permite a las bacterias difundir una señal sobre el medio en el que se encuentran, y así modificar su comportamiento en función de la concentración que existe de esta señal. La …
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Molecular and transcriptomic studies of quorum sensing in Chromobacterium subtsugae
… provide evidence for a novel function of the quorum sensing system. C. subtusgae can sense the presence of competitors by through non-cognate AHL molecules and express genes to design an attack against those competitors.
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Transcriptional Control during Quorum Sensing by LuxR and LuxR Homologues
Quorum sensing is a mechanism used by many proteobacteria to regulate expression of target genes in a population-dependent manner. The quorum sensing system of Vibrio fischeri activates the luminescence (lux) operon when the autoinducer signaling molecule (N-3-oxohexanoyl homoserine lactone) is …
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Structure–Activity Analysis of Peptide-Mediated Quorum Sensing in Streptococcus mitis
… promote resistance through selective pressure, quorum sensing (QS)-targeted therapies disrupt bacterial communication systems that regulate virulence, biofilm formation, and resistance acquirement through competence without directly killing the bacteria. In this study we examined QS modulation …
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Investigating Microbial Quorum Sensing Potential for Enhanced Production of Biodegradable Polymers
… potential usage. However, the manipulation of quorum sensing circuits has yet to be explored in the context of increasing the amount of PHA produced by bacterial species. Quorum sensing is a process of cell-to-cell communication, that allows for bacteria to share information about cell …
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Identification of Quorum Sensing Genes in Halococcus Hamelinensis SP. Nov. 100Na1
… process of cell-to-cell communication is termed quorum sensing (QS). According to cell density, if a specific threshold concentration of autoinducers is reached, the neighboring cells are able to detect and respond to the signal. The phenomenon of QS can control different biochemical processes …
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Reconstitution and Mechanistic Studies on the Staphylococcal agr Quorum Sensing Circuit
<p>Quorum sensing (QS) plays a central role in virulence induction in the commensal pathogen, Staphylococcus aureus. This bacterium secretes an auto-inducer peptide (AIP), a small, cyclic peptide containing a thiolactone linkage as an indicator of its population density, and up-regulates virulence …
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Rgg2/Rgg3 Quorum Sensing in Streptococcus pyogenes and Innate Immune Cell Responses
… are all suppressed. Expression of the Rgg2/Rgg3 quorum sensing system allows S. pyogenes to suppress these innate immune responses. Altogether, the results from these chapters explores how the immune system and microbial pathogens interact with each other to try and come out on top.
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Quorum sensing for improved production of industrially useful products from filamentous fungi
Quorum sensing (QS) is a cell density dependant phenomena utilized as a communication process among microorganisms to regulate their physiological responses. QS depends on the production and release of low molecular weight, diffusible chemical signalling molecules, known as quorum sensing molecules …
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Mechanism of Signal Transduction By The Staphylococcus Aureus Quorum Sensing Receptor AGRC
… out by the accessory gene regulator (agr) quorum sensing system. The agr autoinducing peptide (AIP) pheromone activates the AgrC receptor histidine kinase, resulting in downstream modulation of virulence factor expression. As S. aureus is a dangerous pathogen, understanding virulence …
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