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Showing 1 to 2 of 2 for “"quinic acid derivatives"”.
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Discovery of Quinic Acid Derivatives as Oral Anti-inflammatory Agents
<p>Quinic acid (QA) esters found in hot water extracts of <em>Uncaria tomentosa</em> (a.k.a. Cat’s claw) exert anti-inflammatory activity through mechanisms involving inhibition of the pro-inflammatory transcription factor nuclear factor kappa B (NF-κB). Herein, we described the synthesis and …
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Development and Evaluation of Therapeutics in the Setting of Radiation Injury
… Hot water extracts of Cat’s Claw containing quinic acid have been shown to possess activity in increasing circulating white blood cells as well as promoting DNA repair. Our group previously synthesized and evaluated a series of quinic acid derivatives. Quinic acid derivative KZ-41 was …