Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"quantitative trait locus (QTL) Mapping"”.
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Genetic architecture of multiple disease resistance in one maize chromosome segment substitution line population
… practical chemical control. Thus, we conducted quantitative trait locus (QTL) mapping for BLS resistance in three maize populations: the Z022 (B73 × Oh43 recombinant inbred line) NAM population, the Z023 (B73 × Oh7B recombinant inbred line) NAM population, and the DRIL78 (NC344 × Oh7B chromosome …
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Heritability of Nociception and Antinociception in the Laboratory Mouse
… nociception-related gene(s), we performed quantitative trait locus (QTL) mapping studies of nociception. We found two significant QTLs, associated with chemical/inflammatory nociception, on chromosomes 9 and 10. Also featuring considerable genetically determined variability is pain …
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Characterising the gene regulatory landscape of CD4+ T cells
… how this can lead to autoimmunity. I carried a quantitative trait locus (QTL) mapping using RNA-seq, ATAC-seq, H3K4me3 and H3K27ac ChM-seq data from Tregs isolated from 100 individuals. Additionally, I processed publicly available data from naive T cells to distinguish the Treg specific effects …
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Genome-wide Analyses of Recombination and the Genetic Architecture of Virulence Traits in Cryptococcus
… benign to highly virulent. A wide variety of traits, such as thermal tolerance, melanin production, and an extracellular capsule contribute to virulence, yet our understanding of the genetic architecture of such traits is limited. In the studies reported here, I describe the first genome-wide …
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High-throughput phenotyping and physiological genetics of stomatal patterning and water use efficiency in maize
… robust, and versatile in extracting anatomical traits for multiple cell types on the epidermis. Two years of Quantitative Trait Locus (QTL) mapping in a B73 x MS71 Recombinant Inbred Line (RIL) population for various epidermal traits identified 36 consistent QTL for a given trait in both years, …
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INVESTIGATION OF GENETIC FACTORS DETERMINING ISCHEMIC STROKE OUTCOME
… manner (neuroprotection), we used quantitative trait locus (QTL) mapping on mouse strains that exhibit the most difference in infarct volumes but the least difference in collateral numbers (C57BL/6J and C3H/HeJ). From the F2 B6 x C3H cross, we mapped 4 loci determining infarct …
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Investigations on the influence of CO2 on leaf epidermal development in Arabidopsis thaliana
… plant life cycle and the genetic basis of these traits has been explored by quantitative trait locus (QTL) mapping of an Arabidopsis recombinant inbred (RI) population. In order to quantitatively characterize thousands of Arabidopsis leaf epidermis samples, a new method for high-throughput …
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Variation and quantitative trait loci analysis of myrosinase activity and phenolic compound accumulation in Brassica oleracea var. italica
Made available in DSpace on 2016-03-02T20:24:12Z (GMT). No. of bitstreams: 2 GARDNER-THESIS-2015.pdf: 3191246 bytes, checksum: 282a4f72b0a6003e1ab58dc6ded758c2 (MD5) LICENSE.txt: 4211 bytes, checksum: 9b8349680069b41d9e16d0ea2a47d366 (MD5) Previous issue date: 2015-12-04
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Evaluation and characterization of QTL controlling seed composition in soybean and breeding for resistance to sudden death syndrome of soybean
The first quantitative trait locus (QTL) mapping study in soybean (Glycine max) was published over twenty years ago. Since then numerous QTL mapping studies have been performed for most traits of economic interest within the soybean research community. Though many putative QTL regions have been …
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The generation and maintenance of diversity in a rapid adaptive radiation
… of jaw morphology and a complex functional jaw trait. We use a complex biomechanical system, the 4-bar jaw linkage, to simulate trait evolution during interspecific hybridizations. We find rampant transgression (trait values beyond parental distributions) in jaw function in a large proportion of …
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Overcoming the domestication bottleneck in soybean: mapping domestication traits and using wild soybean to improve diversity
QTL Mapping of Domestication-Related Traits Soybean [Glycine max (L.) Merr.] was domesticated in East Asia from the wild progenitor Glycine soja. The domestication process led to many distinct morphological changes that adapt it to cultivation. These include larger seeds, erect growth, larger stem …
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Metabolic engineering of yeast strains for renewable biomass utilization and valuable chemical production
… Thus, I hypothesized the xylose-utilizing trait is a complex trait which phenotypes result from a multiple genes interaction. Quantitative Trait Locus (QTL) mapping strategy was used to identify ‘hotspots’ in the genome responsible for enhanced xylose utilization. The identified QTLs reveal …
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Dissecting key biomass traits through traditional QTL mapping, exploring novel functional genomics approaches, and investigating self-incompatibility in Miscanthus
… regarding the genetic architecture of the traits integral to yield and adaptability. To address this, a four year quantitative trait locus (QTL) study was conducted on a full-sib, F1 mapping population of M. sinensis segregating for flowering time, height, leaf width, and yield using a …
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Functional genomics of plant compensatory responses
… such plants are termed as tolerant. This trait motivated many empirical studies demonstrating that herbivore damage can, under certain circumstances, increase, rather than decrease, plant reproductive success (a specialized case termed overcompensation, i.e., increased flower, fruit, and …