Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"quantitative biology"”.
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Characterizing the landscape of aminoacyl-tRNA synthetase protein production in Bacillus subtilis
… and provides a framework for future study in quantitative biology.
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Defining the Precision and Sequence Determinants of Protein Synthesis Rates
… controlled is therefore a central question of quantitative biology. In this work, I explore both the degree of precision in protein production and the mechanisms by which protein synthesis rates are encoded in genome sequences. First, I explore whether proportional synthesis of protein complex …
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The Diversion of Macromolecular Synthesis in L-Cells Towards Ends Dictated by Mengovirus
… development of methods of cell culture and of quantitative virology. The solution of these problems, through the painstaking work of T. Puck, H. Eagle, R. Dulbecco and their associates, has made possible the recent rapid advance in our knowledge of the rare intimate details of cell and virus …
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How to build a chordate: Multiscale decomposition of axial morphogenesis in the amphioxus, Branchiostoma lanceolatum
… axial progenitor cell types in amphioxus using quantitative in situ imaging of gene expression, and a bespoke in silico pipeline for cell state classification and spatial mapping. Here, aided also by in vivo signalling perturbations, I locate a population of vertebrate-like neuromesodermal …
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"Gene regulation in Escherichia coli beyond the ""rate"" approximation"
The blueprint of a living cell is inscribed in its DNA. A region of DNA encoding a protein is called a gene. The cell reads the DNA and makes molecular machines made up of proteins to carry out all cellular functions required for survival. All cells live in ever-changing environments, and have …
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On the coupling of noisy processes in biology to produce functional phenotypic variability
Noise is ubiquitous in biology. Recent studies have demonstrated that both gene expression and physiological processes, such as growth, can be noisy. The cell-to-cell variation resulting from this stochasticity has been implicated in survival strategies for bacterial populations. However, it …