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Showing 1 to 20 of 137 for “"pyrophosphate"”.
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Glutamine Phosphoribosyl Pyrophosphate Amidotransferase From Bacillus Subtilis
Made available in DSpace on 2014-12-14T04:27:47Z (GMT). No. of bitstreams: 1 7913663.pdf: 4656709 bytes, checksum: 461aee54ab59f2ed0c2e40bce3810c47 (MD5) Previous issue date: 1978
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Identification and analysis of Arabidopsis thiamine pyrophosphate transporters
Thiamine pyrophosphate (TPP) serves as a cofactor in universal metabolic pathways, including glycolysis, the pentose phosphate pathway (PPP) and the tricarboxylic acid cycle; moreover, it is essential for the proper functioning of all organisms. Recently, several steps of the plant thiamine …
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Ligand Binding and Catalysis by Phosphoribosyl Pyrophosphate Synthetase
… (R5P), and the inhibitor ADP to phosphoribosylpyrophosphate (PRPP) synthetase from Salmonella typhimurium has been studied by equilibrium dialysis of these compounds labeled with ('32)P. The simplest model that fits the data is the suggestion that the enzyme possesses three distinct binding …
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Farnesyl Pyrophosphate/geranylgeranyl Pyrophosphate Synthase of Toxoplasma Gondii: Its Role in the Parasite Isoprenoid Pathway and as a Target for Bisphosphonates
In summary, this work provides information to understand the isoprenoid pathway in T. gondii by isolation and characterization of an important enzyme in the pathway, TgFGGPS. Identification of TgFGGPS as the molecular target of bisphosphonates in this work provides a key tool for rational-based …
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Inactivation of Glutamine Phosphoribosyl Pyrophosphate Amidotransferase in Bacillus Subtilis
Made available in DSpace on 2014-12-14T04:27:33Z (GMT). No. of bitstreams: 1 7524417.pdf: 4422518 bytes, checksum: 2fcd34aaf1e4447b579382dfd2fa4456 (MD5) Previous issue date: 1975
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Osteoblast Response to Zirconia-Hybridized Pyrophosphate Stabilized Amorphous Calcium Phosphate
… mineralization. Recently, a zirconia-hybridized pyrophosphate stabilized amorphous calcium phosphate (Zr-ACP) has been synthesized which permits controlled release of calcium and phosphate ions and thus is hypothesized to be osteoinductive. Incorporation of Zr-ACP into a highly porous poly(DL …
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Biochemical Characterization of Arabidopsis Enzymes Involved in Inositol Pyrophosphate Biosynthesis
… molecules collectively referred to inositol pyrophosphates are synthesized. Inositol pyrophosphates are an emerging class of "high-energy" intracellular signaling molecules containing one or two diphosphate groups attached to an inositol ring, with suggested roles in bioenergetic homeostasis …
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SPECTROSCOPIC STUDIES OF THE INTERACTION OF ANIONS WITH TRANSFERRIN (NMR, PYROPHOSPHATE)
… of the uptake of iron by transferrin from iron-pyrophosphate indicate that the reaction proceeds via an intermediate mixed ligand complex of the type PP(,i)-Fe-transferrin-CO(,3)('2-). The EPR spectrum of the "intermediate" complex was determined by computer modelling of the kinetic data and …
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Elucidating the function of inositol pyrophosphate signaling pathways in Arabidopsis thaliana
… (VIP) kinases, resulting in inositol pyrophosphates (PP-InsPs). PP-InsPs have high energy bonds and have been linked to Pi maintenance and energy homeostasis in yeast, plants, and mammals. However, the precise mechanism(s) by which PP-InsPs act within plant signaling pathways remains …
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Glutamine Phosphoribosyl Pyrophosphate Amidotransferase From Bacillus Subtilis: Iron-Sulfur Biochemistry and Enzymology
The iron-sulfur prosthetic group of glutamine PRPP amidotransferase was found to be a {4Fe-4S} cluster. In the native enzyme, the cluster exists in the diamagnetic +2 redox state. Treatment of the cluster with oxidants resulted either in no reaction or in oxidative dissolution of the cluster, i.e., …
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The Quaternary Structure and Properties of Phosphoribosyl Pyrophosphate Synthetase From Salmonella Typhimurium
Made available in DSpace on 2014-12-14T04:27:32Z (GMT). No. of bitstreams: 1 7524402.pdf: 6016067 bytes, checksum: 21ba3017eb4db78491e2b4fadb6a6ab5 (MD5) Previous issue date: 1975
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Structural insights into conformationally-gated reactions catalyzed by thiamine pyrophosphate-dependent enzymes
Thiamine pyrophosphate (TPP)-dependent enzymes utilize TPP as a biological carbanion to initiate reactions on substrates with carbonyl carbon(s), such as pyruvate and 2-oxoglutarate, two central metabolites. This thesis presents structural analyses of three TPP-dependent enzymes. Most …
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Ab Initio Study of Amorphous Zeolitic Imidazolate Framework (A-ZIF) and Pyrophosphate crystals
… mechanical and optical properties of five pyrophosphate crystals with very complex structures are studied. Existing structures from single-crystal X-ray diffraction shows short O-H bonds, which are rectified by density functional theory (DFT) calculations. The complex interplay of the minor …
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Inositol Pyrophosphate Phosphatases as Key Enzymes to Understand and Manipulate Phosphate Sensing in Plants
… group of secondary messenger molecules, inositol pyrophosphates (PP-InsP). PP-InsPs and their precursors, inositol phosphates (InsPs), are important for plant abiotic stress responses, hormone signaling, and other stress responses. While PP-InsPs are critical for plant survival, much about the …
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Development of an approach towards the stereoselective synthesis of the cyclobutyl isomer of presqualene pyrophosphate
Restriction data tranferred 2014-07-01T11:13:39-05:00 Original Data Group with Access UIUC Users [automated] Release Date: none Reason: ETDs are only available to UIUC Users without author permission
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Chemistry and Regulation of the Oxygen-Dependent Inactivation of Glutamine Phosphoribosyl Pyrophosphate Amidotransferase From Bacillus Subtilis
The purpose of the experiments presented was to investigate the chemistry and regulation of the oxygen-dependent inactivation of Bacillus subtilis glutamine P-Rib-PP amidotransferase in vitro and in vivo. A detailed description of the physical and chemical changes occurring in purified …
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Regulation of 5-Phosphoribosyl-1-Pyrophosphate Synthesis in Salmonella Typhimurium in Vivo: Deductions From Pool Measurements
Made available in DSpace on 2014-12-14T04:27:38Z (GMT). No. of bitstreams: 1 7715010.pdf: 3991775 bytes, checksum: e25c1fefe60df4cdd7d1d59534229a7a (MD5) Previous issue date: 1977
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An investigation into the partial oxidation of C-4 alkanes over vanadyl pyrophosphate and heteropoly acids
… functionalisation were studied: the vanadyl pyrophosphate catalyst for the conversion of n-butane to maleic anhydride and the heteropoly acid catalyst for the conversion of isobutane to methacrylic acid.
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Thiol-Ene Click Chemistry for Solid State Triplet-Triplet Annihilation Upconversion and Parts-Per-Billion Pyrophosphate Sensing in Artificial Seawater
… a conjugated polyelectrolyte (CPE) used as a pyrophosphate (PPi) sensor in complex aqueous media. Chapter I focuses on the synthesis and upconversion performance of rubbery networks fabricated using thiol-ene click photopolymerization. The advancement of triplet-triplet annihilation based …
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Rearrangements of 1-Heterosubstituted Chrysanthemyl Aldehyde and Chrysanthemyl Amines
… the mechanism for the conversion of presqualene pyrophosphate to squalene involves postulation of a new intermediate (known locally as protosqualene pyrophosphate) which is a ring expanded analog of presqualene pyrophosphate. There is no direct evidence for this discrete new intermediate but a …
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