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Showing 1 to 20 of 200 for “"pyrene"”.
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Sensitive Electrochemical Detection Platforms for Anthracene and Pyrene
Der elektrochemische Nachweis von polycyclischen aromatischen Kohlenwasserstoffen (PAK), zu denen Anthracen und Pyren gehören, bietet eine kostengünstigere, einfachere und schnellere alternative Analysemethode als herkömmliche Methoden wie GC und HPLC. Im Vergleich zu diesen Methoden weist er …
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Studying Collagen with PyrATS: Pyrene-Appended Trimeric Systems
… tagged at their N-termini with the fluorophore pyrene. When in close contact, pyrene units can form excimers that emit low-energy light. This allows for the study of several fundamental questions in collagen research using fluorescence spectroscopy, including concentration dependence, folding …
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Effect of Dietary Factors on Mutagenesis, Metabolism, and Binding to DNA of Benzo [a] pyrene and Benzo [a] pyrene 7, 8-dihydrodiol
… inhibited rat liver S9 protein dependent benzo[a]pyrene (B[a]P)-induced mutagenesis in Salmonella typhimurium TA 100 by 30-81% and B[a]P 7,8-dihydrodiol (DHD)-induced mutagenesis by 29 to 75%. EA (5-40 juM) did not significantly affect the metabolism of B[a]P or B[a]P 7,8-DHD as determined by high …
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Benzo[a]pyrene effects on Fundulus heteroclitus reproductive endpoints
Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) that modulates aromatase enzyme function and, thus, potentially interrupts normal reproductive function. The aim of this study was to use a fish model, Fundulus heteroclitus, to assess whether BaP exposure adversely impacted …
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The metabolic fate of benzo [a] pyrene in vivo
[³H]-B[a]P absorption, distribution, metabolism, excretion and macromolecular binding in male Sprague-Dawley rats were investigated following administration by intratracheal instillation through a cannula. [³H]- radioactivity in various organs was determined at timed intervals between 5 and 360 …
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Benzo(a)pyrene control and transport processes in smoke meat products
El incremento del consumo de carne y productos cárnicos en el mundo, así como su proyección en los países en desarrollo y desarrollados, ha estimulado la investigación de su impacto en la salud humana. Los productos cárnicos son componentes importantes de una dieta saludable y balanceada, …
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Effects of benzo[a]pyrene and CYP19a1b knockdown on zebrafish development
<p>Benzo[a]pyrene (BaP) is a ubiquitous environmental contaminant that is both an endocrine disruptor and a carcinogen. Aromatase (CYP19) is a key enzyme in steroidogenesis playing a key role in the hypothalamus-pituitary-gonad feedback loop. We hypothesized that BaP would negatively impact …
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Pyrene Butyric-Protein Conjugates: A New Fluorescent Chromophore for Protein Studies
Made available in DSpace on 2014-12-09T17:35:51Z (GMT). No. of bitstreams: 1 6801792.pdf: 5545890 bytes, checksum: 5e9fd82892913b4eeb3da47107ec4d83 (MD5) Previous issue date: 1967
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DNA adducts as molecular biomarkers of exposure to benzo(a)pyrene
Thesis (Ph. D.)--Massachusetts Institute of Technology, Division of Toxicology, 1997.
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Laboratory study of the atmospheric heterogeneous oxidation of benzo[a]pyrene
… heterogeneous reaction of particle-phase benzo[a]pyrene (BaP) with atmospheric oxidants ozone (O₃) and hydroxyl radical (OH) was investigated by simulating atmospheric conditions in a laboratory environmental chamber and measuring the particle-phase species with an Aerodyne Mass Spectrometer …
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Photophysical properties of pyrene, 2,7 diazapyrene and 1,3-bis(β-naphthyl)propane.
… of Van Der Waals' dimers and clusters of pyrene and diazapyrene have been investigated. Excimers, dimeric species which are associative in an excited electronic state and dissociative in their ground state, have long been established and play an important role in many areas of …
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Epigenetic effects of benzo(a)pyrene in Fundulus heteroclitus and Danio rerio
… Danio rerio (zebrafish), to study the benzo(a)pyrene (BaP) effects on DNA methylation status and whether the alterations could contribute to BaP-mediated reproductive and developmental toxicities. Initially, we used Fundulus to study BaP effects on glycine N-methyltransferase (GNMT) expression …
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Synthesis and chemosensing ability of novel pyrene-isoxazole-calix[4]arene constructs
… built up of the following elements: a pyrene reporter unit, an isoxazole unit functioning as linker and ion-binding moiety and calixarene scaffold as ion-binding moiety - PIC.
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CATALYTIC BORYLATION OF C-H BONDS: A ROUTE TO PHOTOPHYSICALLY INTERESTING PYRENE DERIVATIVES
Pyrene derivatives have found use in a wide range of applications that make use of the unique structural, optical and charge-transfer properties of pyrene. Nearly all pyrene derivatives are substituted at the 1-, 3-, 6- and 8-positions, i.e. the sites of electrophilic aromatic substitution. In …
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Quantification of benzo[a]pyrene-diol-epoxide adducts by laser-induced fluorescence spectroscopy
… were used to quantify adducts of benzo[a]pyrene-7,8-diol-9,10- epoxide (BPDE) in human lung tissue and human bronchial epithelial cell histones and DNA and in human serum albumin. The presence of BPDE adducts in human lung tissue and human bronchial epithelial cell histones and DNA was …
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Characterization of cyclopenta[cd]pyrene-DNA adducts in vitro and in mice in vivo
Thesis (Ph. D.)--Massachusetts Institute of Technology, Division of Toxicology, 1996.
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Synthesis, Linear and Nonlinear Photophysical Characterization of Two Symmetrical Pyrene-terminated Squaraine Derivatives in Solution
Two indole-based squaraine dyes bonded to two pyrenyl groups through vinyl- and ethynyl- linkers were synthesized with the aim of enhancing the intramolecular charge transfer interaction in addition to improving their optical properties. The absorption and emission properties of these derivatives …
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Fluorescence Decay of Pyrene Butyric Acid Attached to Macromolecules: A Study by Pulsed Laser Excitation
Made available in DSpace on 2015-05-12T21:41:55Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7013526.PDF: 4524942 bytes, checksum: 31e69bc088c2804aa8e6d815ab9feee6 (MD5) Previous issue date: 1969
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