Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"pyramidal neuron"”.
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Cortical Pyramidal Neuron Subtype Classification and Visual Response Diversity
… and computation. The classification of pyramidal neurons into functional subtypes remains a crucial part of this survey since the subtype-specific division of labor creates a rich substrate for computation. However, the extreme integration of individual neurons into the collective cortex …
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Knockout of the glutamate transporter GLT-1 specifically from neurons drastically alters transcriptome profiles in CA3, CA1, and Striatum
… with excitatory terminals, particularly in CA3 pyramidal neuron axon terminals within CA3 and CA1 as well as in cortical layer V pyramidal neuron axon terminals within striatum. The specific functions of GLT-1 in axon terminals in regulating glutamate homeostasis and synaptic transmission are …
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Distinct Populations of Layer 5B Pyramidal Neurons in the Primary Motor Cortex
… depends on the coordinated activity of many neurons found across its laminar structure. Layer 5b (L5b), a deep cortical layer that drives output signals from the cortex, contains excitatory pyramidal neurons that innervate many subcortical areas of the brain. In the motor cortex, L5b is …
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Cellular and Synaptic Morphology of Golgi -Impregnated Cortical Neurons in Patients With Schizophrenia
… reveal that despite normal numbers of cortical neurons, patients exhibit anatomical reductions in synaptic connectivity. Prefrontal regions have been implicated as a site of vulnerability to pathophysiological alterations, while evidence of anatomical disturbances in other cortical regions …
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Investigating cestode modulation of host neuronal excitability and cell-type-specific gene expression in an in vitro mouse model of neurocysticercosis
… it had little impact on genes modulating neuronal excitability. This was corroborated by whole-cell patchclamp data demonstrating no LPS-induced changes in the intrinsic electrical properties of pyramidal neurons. In the second part of the thesis, I exposed mouse hippocampal OBSCs to a T. …
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Mechanisms underlying neural circuit remodeling in Toxoplasma gondii infection
… to assess cell-to-cell connectivity and neuron-glia interactions (including immunohistochemistry, ultrastructural microscopy, and microglia-specific reporter mouse lines), I discovered that longterm Toxoplasma infection causes microglia to target and ensheath neuronal somata in these …