Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 1 of 1 for “"punctuated evolution"”.
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A Pan-Cancer Single-Cell Analysis of Intratumoral Copy Number Diversity and Evolution
… of intratumoral heterogeneity (ITH) and its evolutionary dynamics remain poorly understood.</p> <p>To address these gaps, we developed Acoustic Cell Tagmentation (ACT), an advanced single-cell single-molecule DNA sequencing (scDNA-seq) technology, to resolve the copy number substructure of …