Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"pulmonary valve"”.
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Pulmonary Valve Replacement
<p>Currently, transcatheter pulmonary valve replacement (TPVR) is a well-established alternative for surgical pulmonary valve replacement (SPVR) to treat pulmonary valve disorders in patients with prior congenital heart surgery. Edwards Sapien 3 valve is a bioprosthesis originally designed for the …
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Dobutamine stress magnetic resonance imaging in tetralogy of fallot
… long-term effects of TOF repair, chronic severe pulmonary regurgitation (PR) continues to be considered one of the most important as this has detrimental effects on cardiac function with a risk of sudden cardiac death. The optimal timing of pulmonary valve replacement remains controversial and …
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CD133 Antibody Conjugation to Decellularized Human Heart Valves For Circulating Endothelial Progenitor Cell Capture
The long term efficacy of heart valve bioprostheses is limited by progressive degeneration characterized by immune mediated inflammation and calcification. To avoid this degeneration, decellularized heart valves with functionalized surfaces capable of rapid in vivo endothelialization have been …
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Early prototyping and testing of a model of an expandable heart valve apparatus for paediatric deployment
… which involves one or more of the heart valves - the aortic and mitral valves on the left and the pulmonary and tricuspid valves on the right. Valves diseases in infants are congenital and their effect is to burden the heart with an increased work to maintain the stroke volume what might …
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Genetic investigation of South Africans with the Noonan Syndrome phenotype using targeted next generation sequencing
… series, our cohort revealed a lower frequency of Pulmonary Valve Stenosis (34.6%) and a less severe developmental phenotype. Variants predicted pathogenic were detected in 7(43.7%) DNA samples out of the 16 analysed. The genes involved were CBL in three cases (42.8%), PTPN11and MAP2K1in two cases …
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Development of a Tubular Biological Tissue-Engineered Heart Valve with Growth Potential
… immunogenicity. An allogeneic tubular heart valve was fabricated by inserting one engineered tube inside of another and attaching them together using degradable sutures. Extensive hemodynamic testing was performed in order to optimize and verify valve design. The growth potential and in vivo …