Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"pulmonary epithelium"”.
-
Stem and Progenitor Cells in Homeostatic Maintenance and Perturbation of the Pulmonary Epithelium
… from a normal pseudostratified airway epithelium to lung squamous cell carcinoma in situ are well documented. However, the contribution of mutated tissue stem or progenitor cells to this process are poorly understood at the level of clonal resolution. Secretory cells are known …
-
Accelerated Maturation of Fetal Alveolar Epithelium in New Zealand Rabbits After Single Maternal Injections of Solu-Medro
… in premature infants as a result of an immature pulmonary epithelium. In utero fetal injections of glucocorticoids accelerate the maturation of the alveolar epithelium. Recent studies indicate that maternal injections of certain glucocorticoids may also be effective. To examine this further, …
-
The role of Serum- and Glucocorticoid kinase in the hormonal control of sodium transport in pulmonary epithelia
… However, SGK1 knockout mice do not display any pulmonary abnormalities. Thus the role that SGK1 plays is not fully understood. In this thesis I have explored the role of this kinase in dexamethasone-induced ENaC activity in the H441 human bronchiolar cell model. Dexamethasone-deprived cells do …
-
Transcriptional Regulation of Cardio-Pulmonary Development
… epithelial cells (Clara cells) in the distal epithelium may explain the hypercellularity observed in btf-null lungs. These results show that Btf is required for normal maturation and patterning of the pulmonary epithelium and survival of the animal.
-
Alveolar stem cell dynamics and regulatory mechanisms in homeostasis and early oncogenesis
… cells, which act as stem cells in the alveolar epithelium, have been identified as key cells of origin of LUAD, little progress has been made in understanding the precise sequence of events that transform single AT2 cells into complex malignant tumours. Here, I trace thousands of individual …
-
Polymeric Nanocarriers And Their Oral Inhalation Formulations For The Regional Delivery Of Nucleic Acids To The Lungs
… acids to the lungs to treat medically relevant pulmonary disorders, such as COPD, asthma, virus infections, cystic fibrosis, and lung cancer.</p>