Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 74 for “"public health challenge"”.
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Shiga Toxin-Producing Escherichia coli: a Public Health Challenge in the Pre-Harvest Stage of the Farm-to-Table Continuum
Escherichia coli is part of the normal gastrointestinal microbiota of many animals, especially cattle. While most strains are commensal, Shiga toxin-producing E. coli (STEC) can cause severe human illness. Pathogenicity of STEC is associated with genes such as those encoding Shiga toxins, …
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Paediatric and Adolescent civilian gunshot injuries: a 10 year epidemiological study
… involving firearms, poses a significant public health challenge, particularly when it affects children. Previous studies showed a decrease in paediatric civilian gunshot injuries following the introduction of the 2004 Firearms Control Act. This study examines the epidemiological trends of …
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Pertussis: Advances in Vaccine Development and Disease Control Strategies
… by Bordetella pertussis, remains a significant public health challenge despite widespread vaccination programs. This thesis explores advancements in vaccine development and disease control strategies. It emphasizes virulence factors such as Vag8, SphB1, BrkA, and BapC as potential components for …
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Multi-site sampling and risk prioritization of antibiotic resistance genes in sewage environments
… human and environmental habitats is a global public health challenge. In this study, we investigate the public health relevance of antibiotic resistance found in wastewater by combining metagenomic sequencing of wastewater environments with risk prioritization of resistance genes. We find that …
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Data integration for the analysis of uncharacterized proteins in Mycobacterium tuberculosis
… controlling the disease, tuberculosis remains a public health challenge. The contribution of existing drugs is of immense value, but the deadly synergy of the disease with Human Immunodeficiency Virus (HIV) or Acquired Immunodeficiency Syndrome (AIDS) and the emergence of drug resistant strains …
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A machine learning model of Manhattan air pollution at high spatial resolution
… understanding and predicting it is a significant public health challenge. A neural network NARX model was created in MATLAB for each cell on a 250m square grid laid over Manhattan, for a total of 907 individual models across the city, for PM2 .5 , CO, NO2 , 03, and SO 2. In addition to standard …
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The Impact of Pain on Key Outcomes in Opioid Use Disorder Recovery
… misuse and addiction constitute a significant public health challenge in the 21st century, with opioids involved in the majority of drug overdose deaths since 1999. A vigorously researched area that contributes substantially to the opioid misuse and addiction challenge is pain. The impact of …
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Smartphone-based systems for mobile infectious disease detection and epidemiology
Infectious diseases remain a serious public health challenge worldwide and are the leading cause of death in many developing countries. The rapid detection of pathogens is vital for the control and prevention of the infectious diseases. New tools are needed to enable rapid detection, …
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Social determinants of health in patients with congenital rare disease
Rare and orphan diseases represent a substantial public health challenge, yet population-level evidence describing how social determinants of health, institutional context, and patient experience shape outcomes remains limited. Although rare diseases are often framed primarily through genetic and …
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Addressing Barriers to Preventive Healthcare Access Through Community Outreach in Underserved Populations
<p>Access to preventive healthcare is a significant public health challenge, particularly for underserved populations in Muscogee County, Georgia. This project addresses systemic barriers such as transportation, limited health education, and economic constraints, which contribute to health …
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Preventing Opioid Overdose: From Prediction to Operationalization
The opioid epidemic remains a significant public health challenge in the US. A potential catalyst for reducing the incidence of opioid-related harm is the development and operationalization of risk stratification models. Prior work has focused on the statistical performance of such models without …
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Are Post-Transcriptional RNA Modification Events in the Glutamate-Gated and GABA-Gated Chloride Channels of Anopheles minimus and Anopheles dirus associated with Ivermectin Insensitivity?
… most notably malaria, have been a constant public health challenge in many regions around the world claiming the lives of hundreds of thousands every year. Vector control strategies such as insecticide use were initially effective in reducing malaria transmission. However, the emergence and …
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Exploring barriers to TB contact tracing and screening: health service providers’ perspective
Tuberculosis (TB) continues to be a global public health challenge, with South Africa experiencing one of the highest TB incidence rates worldwide, exacerbated by its intertwined battle with and the emergence of drug-resistant TB strains. The study conducted in iBhayi Township, Eastern Cape …
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Association Between Socioeconomic Status (SES) and Obesity Among Adults: A Systematic Literature Review
Obesity has emerged as a critical global public health challenge, contributing significantly to morbidity, mortality, and economic costs. Its development is shaped by a complex interplay of biological, behavioural, and environmental factors, yet socioeconomic status (SES) remains a central …
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Non-Definitive HIV Test Results: The Impact of Non-Definitive HIV Test Results at a Metropolitan Academic Not-for-Profit Integrated Health Care System (MANIHCS) HIV Test Site
… metropolitan academic, not-for-profit integrated health care system. The Centers for Disease Control and Prevention (CDC) 2012, estimated that 1.8 million individuals in the U.S. were infected with HIV. In 2013 the state of Georgia had a total of 77,654 individuals living with HIV/AIDS; an …
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Exploring the Service Providers' and Former Service Users' Perceptions of the Effect and Impact of Living Hope Community Based Substance Abuse Rehabilitation of South Peninsula, Cape Town
Substance use remains a significant global public health challenge. This growing issue has extensive consequences, impacting health, crime, exacerbating socio-economic issues, and the spread of HIV/AIDS. In South Africa, the prevalence of substance use, involving alcohol, cocaine, and dagga, is a …
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Toxicological Analysis of Tacrines and Verapamil on the Yellow Fever Mosquito, Aedes aegypti
Mosquitoes affect human health worldwide as a result of their ability to vector multiple diseases. Mosquitocide resistance is a serious public health challenge that warrants the development of improved chemical control strategies for mosquitoes. Previous studies demonstrate the mosquito blood-brain …
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BRFSS 2015-2017: Exploring the Burden of Caring For Others
Recognizing the growing public health need for informal care, the U.S. Centers for Disease Control & Prevention (CDC) commissioned an expert panel to develop a “caregiver module” for the Behavioral Risk Factor Surveillance System (BRFSS), the CDC’s annual health survey. The new module was piloted …
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Knowledge, attitutes and practices of medical doctors on pharmacotherapy for smoking cessation in Khomas region, Namibia
… diseases and remains a significant public health challenge in many lower and middle income countries (LMIC). Inspite that smoking cessation (SC) pharmacotherapy significantly reduces poor outcome, access to smoking cessation services in medical practice in Namibia is unknown. The …
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Implementation of a Fruit and Vegetable Voucher Program in San Francisco
<p>Chronic disease has emerged as the predominant public health challenge of the 21st century. Chronic diseases like cardiovascular disease, cancer, type 2 diabetes and obesity have maintained their top positions as the leading causes of poor health, disability, death, and high health-care …
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