Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"protrudin"”.
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The interconnected roles of spastin and protrudin in endosomal sorting
… the functional interaction of spastin and protrudin and found that protrudin, an ER-associated adaptor molecule involved in anterograde membrane traffic, is a novel factor regulating endosomal tubule fission in non-polarised cells and in human iPSC-derived neurons. This required protrudin’s …
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Investigating protrudin’s role in neuroprotection and axon regeneration in the central nervous system
Protrudin — a transmembrane scaffold protein found in tubular regions of the endoplasmic reticulum (ER) — has previously been shown to strongly promote neuronal survival and axon regeneration after central nervous system (CNS) injury. This is in part due to increased levels of integrins in the …
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Promoting Central Nervous System Regeneration by Targeting Intracellular Pathways
… to restore axon transport of growth-molecules, protrudin - a membrane-associated protein involved in directional membrane trafficking, was studied. Phosphorylated protrudin preferentially binds Rab11, a small GTPase involved in axon transport of growth receptors. This association is required for …