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Showing 1 to 20 of 22 for “"protoporphyrinogen oxidase"”.
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Studies on human protoporphyrinogen oxidase
This study examines the effects of various protoporphyrinogen oxidase mutations responsible for variegate porphyria, the role of the arginine-59 residue, and the glycines in the conserved flavin binding site, in catalysis and/or cofactor binding. Wild type recombinant human protoporphyrinogen …
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Mitochondrial targeting of wild-type and mutant human protoporphyrinogen oxidase (PPOX)
Bibliography: 140-197 leaves .
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Characterisation of the flavin adenine dinucleotide binding region in Myxococcus xanthus protoporphyrinogen oxidase
This dissertation focuses on protoporphyrinogen oxidase (PPOX), the penultimate enzyme in the haem biosynthetic pathway. Partial defects in PPOX result in variegate porphyria, an autosomal dominant disorder. PPOX catalyzes the six electron oxidation of protoporphyrinogen IX to protoporphyrin IX, in …
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Avoiding Protoporphyrinogen Oxidase Inhibiting Herbicide Selection Pressure on Common Ragweed and Palmer amaranth in Soybean
… and ALS-inhibiting herbicides, growers rely on protoporphyrinogen oxidase inhibiting herbicides (PPO) such as flumioxazin applied preemergence (PRE) and fomesafen postemergence (POST) to control both weeds. Experiments were conducted with the overarching goal of reducing PPO selection pressure …
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A CHARACTERIZATION OF SELECTION FOR EVOLVED RESISTANCE TO PROTOPORPHYRINOGEN OXIDASE (PPO)-INHIBITING HERBICIDES IN AMARANTHUS TUBERCULATUS
… foliar applications of herbicides that inhibit protoporphyrinogen oxidase (PPO; EC 1.3.3.4) activity (PPO-R). Herbicides within this site of action (WSSA site of action #14) remain efficacious when soil-applied to PPO-R waterhemp populations. Therefore, the continued use of these herbicides for …
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Exploring the mechanisms of Palmer amaranth resistance to protoporphyrinogen oxidase-inhibitor herbicides, dynamics of gender, and management strategies
… mechanism(s) conferring resistance to protoporphyrinogen oxidase (PPO)-inhibitors (e.g., lactofen and fomesafen) in a multiple-resistant Palmer amaranth population from Kansas (KCTR), 2) compare female and male life cycles of Palmer amaranth to identify differences that could be …
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Variegate porphyria : molecular aspects of variegate porphyria in South Africa and their biochemical and clinical consequences
… with a deficiency of the haemsynthesising enzyme protoporphyrinogen oxidase (PPO). VP is one of the commonest monogenic inherited disorders in South Africa. The clinical effects include photocutaneous sensitivity and the development of potentially life-threatening acute porphyric crises. Section 1 …
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Expression, purification and characterisation of protoporphyrinogen oxidases from diverse species
This work involved the characterisation of protoporphyrinogen oxidase (PPO), the penultimate enzyme in haem biosynthesis, from Bacillus subtilis, Myxococcus xanthus, and human. A defect in human PPO causes variegate porphyria, an autosomal dominant disorder characterised by skin photosensitivity …
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Population genetics of herbicide resistance in waterhemp
… populations resistant to herbicides that inhibit protoporphyrinogen oxidase (PPO) have been identified throughout the Midwest and the mechanism of resistance in populations from Illinois was previously determined to result from a 3 base pair deletion in the protoporphyrinogen oxidase …
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Control and Fecundity of Palmer Amaranth (Amaranthus palmeri) and Common Ragweed (Ambrosia artemisiifolia) from Soybean Herbicides Applied at Various Growth and Development Stages
… inhibiting herbicides resulting in the use of protoporphyrinogen oxidase- (PPO) inhibitors to control these biotypes, although PPO-resistant biotypes are increasing. New soybean herbicide-resistant trait technologies enable novel herbicide combinations. Combinations of two herbicide …
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Evaluating cover crops and herbicides for horseweed and Palmer amaranth management
… (3) Palmer amaranth control in response to three Protoporphyrinogen Oxidase (PPO) inhibitors applied every three days once Palmer amaranth plants reached 2.5 cm tall. Cereal rye reduced weeds biomass by 78% and weed density by 75% by 8 weeks after cover crop seeding in the fall. At cover crop …
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Multiple Herbicide Resistance in Waterhemp
… and a POST application of lactofen, a protoporphyrinogen oxidase (PPO)-inhibiting herbicide. Greenhouse studies were conducted with this waterhemp biotype, and revealed that plants were also resistant to atrazine, a photosystem II (PSII)-inhibiting herbicide. A waterhemp line selected …
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GENETICS OF GROUP 14 HERBICIDE TOLERANCE IN LENTIL
… site of sulfentrazone and fluthiacet methyl, protoporphyrinogen oxidase genes were sequenced across multiple lentil genotypes. Several single nucleotide polymorphisms (SNPs) were detected to cause amino acid substitution in target enzymes. Based on single marker analysis, one SNP was found to …
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Characterization of a novel five-way-resistant population of waterhemp (Amaranthus tuberculatus)
… 5-enolpyruvyl-shikimate-3-phosphate (EPSPS), protoporphyrinogen oxidase (PPO), TIR1 auxin receptor, Photosystem II (PSII), and 4-hydroxyphenylpyruvate dioxygenase (HPPD). In 2012, a grower reported the failure to control a waterhemp population in conventional white corn with topramezone, an …
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Mechanism of Resistance in Common Ragweed to PPO-inhibiting Herbicides
… One particular herbicidal class is known as the protoporphyrinogen oxidase (PPO, Protox) inhibiting herbicides. Only four weed species have been documented with resistance to this herbicide class. Waterhemp was the first weed species documented with PPO-resistance, which was due to a single codon …
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Characterization of HPPD-inhibitor resistance in waterhemp (Amaranthus tuberculatus)
… inhibitors, while glyphosate, glufosinate, and protoporphyrinogen oxidase (PPO) inhibitors generally provide the greatest control of this population. Chapter 4 discusses the efficacy of various soil-applied residual herbicides to determine appropriate control options for the McLean Co. waterhemp …
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Characterization of PPO-inhibitor resistance in waterhemp (Amaranthus tuberculatus) and Palmer amaranth (Amaranthus palmeri)
… of resistance to these herbicides and, thus, protoporphyrinogen oxidase (PPO) inhibitors were used to help control these resistant weeds. Waterhemp was the first weed species to evolve resistance to PPO inhibitors, and Palmer amaranth evolved resistance ten years later. The first known …
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Preemergence activity of chloroacetamide herbicides on a multiple herbicide-resistant population of waterhemp (amaranthus tuberculatus)
… (EPSPS) inhibitors, protoporphyrinogen oxidase (PPO) inhibitors, synthetic auxins, Photosystem II inhibitors (PSII), and 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitors. Chloroacetamide herbicides, however, have remained effective. During research on the first …
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Herbicide-based Weed Management Systems for Potato (<i>Solanum tuberosum</i>) and Wheat (<i>Triticum aestivum</i>) and Growth and Reproductive Characteristics of Smooth Pigweed (<i>Amaranthus hybridus</i>)
… Since the site of action of sulfentrazone, protoporphyrinogen oxidase, is located in shoot tissue, translocation to shoots is essential for sulfentrazone toxicity. Therefore, the proposed primary mechanisms of selectivity between these species are differential root absorption and …
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Discovery, surveillance, and management of herbicide-resistant amaranthus spp
… synthase (EPSPS) and protoporphyrinogen oxidase (PPO), have become widespread within a narrow subset of the Amaranthus genus, such as A. tuberculatus and A. palmeri. Species within the genus possesses a distinct geographic distribution. Maintenance of these geographical …
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