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Showing 1 to 1 of 1 for “"proteotoxic stre"”.
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MOLECULAR MECHANISMS ORCHESTRATING LYSOSOME-MEDIATED DEGRADATION OF RIBOSOMES IN ANEUPLOID CELLS
… cell physiology, causing a plethora of cellular stresses. One of the most prominent effects of abnormal karyotypes is the development of proteotoxic stress, which is characterised by the aggregation of aberrant proteins in the cytoplasm. The disruption of protein homeostasis correlates with and …