Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 32 for “"proteins/peptides"”.
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Labeling of Proteins, Peptides, and Estrogens With Cyclopentadienyltricarbonylrhenium and Technetium
The conjugation of cyclopentadienyltricarbonylrhenium to molecules having an affinity for the estrogen receptor is described. A variety of derivatives were prepared using either an indirect labeling or a preformed chelate approach, and of the compounds synthesized, …
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Mass Spectrometric Analysis of Thiol Proteins/Peptides Following Selenamide Derivatization And Electrolytic Reduction of Disulfide Bonds
… electrolytic reduction of disulfide-containing peptides/proteins. In addition, electrochemistry (EC) can assist the top-down characterization of proteins by electrolytic reduction of the disulfide bonds, in which sequence coverage can be significantly improved for electron-capture dissociation …
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Soil Organic Nitrogen - Investigation of Soil Amino Acids and Proteinaceous Compounds
… nitrogen (N) are predominantly in organic form. Proteins/ peptides, as an important organic form of N, constitute a substantial part of soil organic matter. On one hand, proteins/peptides are an important N source for plants and microorganisms, particularly in soils where inorganic N is limited. …
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Preparation, characterisation and functional applications of whey protein-carbohydrate conjugates as food ingredients
… and functional properties of whey proteins/peptides conjugated with a range of starch hydrolysis products. Targeted structural modification of the components, e.g., hydrolysis of the whey proteins, or increasing dextrose equivalent value of the starch hydrolysis products, increased …
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Protein Preservation in Fossil Whale Bones of the Miocene/Pliocene Pisco Formation, Peru
… Performance Liquid Chromatography (FPLC) for proteins/peptides size separation. The FPLC fractions were analyzed by Matrix-assisted Laser Desorption/ Ionization-Time of Flight (MALDI-TOF) for a more specific identification of the proteins/peptides sizes. Polyamide sheet Thin-Layer …
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Physicochemical properties of whey protein hydrolysates and their applications in infant formula
… whey protein isolate molecules into Gaussian polypeptides were examined. SAXS is a powerful tool to track protein hydrolysis dynamics and study structural modifications. WPHs produced via bromelain hydrolysis were investigated to stabilise infant formula model emulsions. WPHs with lower degrees of …
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The impact of moisture-induced aggregation of soy protein isolate and hydrolysate during storage on product and nutritional quality
… However, during processing and distribution proteins/peptides tend to aggregate when introduced to increased temperatures and relative humidity. When aggregation occurs in a dry protein powder, there is a decrease in processability, product quality, and consumer acceptability. It is therefore …
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The discovery and functional study of a bioactive peptide, QUB-3273, from the skin secretion of the frog, Odorrana schmackeri
… The main components include alkaloids, steroids, peptides and proteins. Peptides have been found its diverse bioactive roles, such as neurotransmitters, antibiotics and trypsin inhibitors. To solve the severe antimicrobial resistance, antimicrobial peptide gradually becomes a promising agent. …
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Mass spectrometry-based protein profiling strategies for biomarker discovery in liver and inflammatory bowel diseases
… the continuous improvement and combination of proteins/peptides separation techniques, mass spectrometry, statistical and bioinformatic approaches. In this thesis work two different mass spectrometry-based protein profiling strategies have been developed and applied to liver and inflammatory …
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Biomimetic sensor for in-vivo applications
… a specific recognition ligand for detecting proteins in living cell. A molecular sensor for non-nucleic acid analytes (e.g., proteins, peptides, drugs, hormones) can be designed and demonstrated using molecular recognition and design principles analogous in some ways to the molecular switch …
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Experimental and theoretical investigation of the effects of low-frequency sonophoresis on transdermal drug transport
… that are excluded from this category, such as proteins, peptides, and DNA, has stimulated the investigation of various skin permeation enhancement methods, among which ultrasound represents a promising skin permeation enhancer. Previous work by our group has shown that ultrasound at a frequency …
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Cell Wall/Surface Proteome of Candida albicans: its Application in Rapid Identification of Yeast Species by Mass Signature and Characterization by in vitro and in vivo Chemical Labelings
… digestion of the intact fungal cell surface proteins ("whole cell shaving"), biotin-avidin affinity enrichment of biotinylated peptides, liquid chromatography mass spectrometry (LC-MS) based proteomic approach were employed for unambiguous identification of cell wall/cell wall associated …
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The Discovery and Functional Evaluation of a Novel Bioactive Peptide, QUB-3411, from the Frog Skin Secretion of Hylarana guentheri
… been reported to have multiple functions, like proteins, peptides, steroids, alkaloids and biogenic amines. Bioactive peptides, especially the antimicrobial peptides (AMPs) are considered to be promising clinical drug candidates as they are highly effective in defending against various pathogens …
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Development and physical characterisation of polyethylene glycol glycerides-based gel formulations for macromolecule delivery
… on enhancing the bioavailability of protein/peptides. Gelucire 50/13 is a complex mixture of glycerides and PEG. It is mainly used in solid oral formulations for delivering small molecular weight drugs. The purpose of this project was to develop novel uses of Gelucire as a liquid …
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Towards Early State Disease Detection in Microdevices: Fabrication and Testing of Micro Total Analysis Systems for Bioanalytical Applications
… the characterization of the entire complement of proteins, or proteome. Micro total analysis systems (μTAS) are an emerging promising method, offering rapid, sensitive and low sample consumption separations. I have demonstrated microchip capillary electrophoresis (CE) devices made of CaF2. New …
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Characterization of Rheumatoid Arthritis-Specific Immune Responses and Evaluation of a Novel Peptide Immunotherapy in the Collagen Induced Arthritis Mouse Model
… against citrullinated and homocitrullinated proteins/peptides (CitP and HomoCitP). To study RA, mice with collagen induced arthritis (CIA) are commonly used; however, it remains unclear whether this pre-clinical model adequately represents disease-specific autoimmune responses. Therefore, …
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Proteomic Evaluation and Cytotoxicity of Red Maple (Acer rubrum) Leaves
… in cosmetic applications. Plant-derived proteins and peptides are important biomolecules; however to date, there is no published data on the identification of proteins/peptides from red maple leaves. Therefore, the present study focuses on the activity guided purification of proteins from …
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Characterization of Effector Genes in Acidovorax citrulli the Causing Agent of Bacteria Fruit Blotch Disease of Cucurbits
… using Aave2166 identified six N. benthamiana proteins/peptides which specifically interacted with Aave2166. Further characterization of these Aave2166 interactors may allow us to understand the virulence mechanism provided by Aave2166. The identification of nonhost resistance genes that can …
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The Recovery of Protein from Egg Yolk Protein Extraction Granule Byproduct
… with complexes of phosvitin and high density lipoproteins linked by phosphocalcic bridges. In their native form, the proteins are mostly insoluble, however previous studies have shown the links can be broken by alterations in pH, ionic strength, and mechanical treatments. This thesis project seeks …
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Diverse functions of LanC-like proteins in mammalian cells
Bacterial LanC proteins have been extensively studied and shown to be responsible for installing thioether crosslinks in precursors of lanthipeptides. These modifications allow lanthipeptides to possess different biological activities such as antimicrobial activity. LanC-like proteins have been …
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