Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"protein-nucleic acid interactions"”.
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Image Deconvolution Techniques for Single Molecule Studies
… in the field of biophysics, particularly that of protein-nucleic acid interactions, is the need to analyze information from single proteins as opposed to ensembles of many molecules. Consequently, the advent of high-resolution imaging in single molecule microscopy has enabled researchers to probe …
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Machine Learning and Optimization Algorithms for Intra- and Intermolecular Interaction Prediction
… prediction of intra- and intermolecular interactions, specifically intra- protein residue-residue interactions and the interaction sites in between proteins and other macromolecules, are critical for understanding numerous biological processes. The existing methods fall short in …
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Chemical synthesis of DNA and RNA containing thio-substituted bases and their post-synthetic modifications
… been useful tools for studies of carcinogenesis, protein or nucleic acid structures and functions, protein-nucleic acid interactions, and for antisense modulation of gene expression. One successful example has been the synthesis and study of oligodeoxynucleotides containing 6-thio-2'-deoxyguanine. …
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Understanding the physiological role of the small RNA RydC
… shown to stabilize cfa (cyclopropane fatty acid synthase) mRNA, resulting in higher levels of cyclopropane fatty acids in the cell membrane. Here, we show that additional sRNAs, ArrS and CpxQ, also directly regulate cfa post-transcriptionally. RydC and ArrS act through masking an RNase E …