Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"protein-based vaccines"”.
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Development of polymer and lipid materials for enhanced delivery of nucleic acids and proteins
… therapeutics such as nucleic acids and proteins could potentially catalyze the clinical translation of many gene and protein-based therapies. However, progress has been hindered by a lack of safe and effective materials and by insufficient insight into the relationship between key …
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Design of vaccine nanotechnology-based delivery systems, the effect of CpGODN TLR9 agonist-protein antigen conjugates anchored to liposomes
… with liposomes on the immunogenicity of protein-based vaccines has not been explored yet.In this present study, thiol-maleimide chemistry was utilised for the covalent ligation between protein antigen and CpGODN TLR9 agonist, which did not alter protein's ability to be recognised by …
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Adenovirus Vectors as Potent Adjuvants in Vaccine Development
… these immunostimulatory properties of Ad in vaccines to prevent transmission of malaria by Plasmodium falciparum. When combined with vaccines preventing infection, transmission-blocking vaccines (TBVs) could limit the spread of malaria. Our study explores how novel, Ad5-based TBVs enhance the …
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Consistent Fabrication of Ultrasmall PLGA Nanoparticles and their Potential Biomedical Applications
… and gene delivery, biodetection of pathogens or proteins, and tissue engineering. The aim of this study was to fabricate ultrasmall poly-(lactic-co-glycolic acid) nanoparticles (PLGA NPs) using a quick and easy nanoprecipitation method1, with some modifications, for general use in various …