Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"protein stabilisation"”.
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Biologically Inspired Engineering for Protein Stabilisation
… Here, a biologically inspired vaccine stabilisation method is proposed. The method is based on the fact that proteins entrapped in the fossil avian eggshell crystals are well preserved up to thousands of years in Africa where high-temperature vaccine stability is needed. The persistence …
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Characterising mechanisms of regulation of hypoxia-inducible factors.
… pathway mediated by the Hypoxia-inducible factor protein, HIF. HIF is a heterodimer consisting of one of three alpha subunits (HIF-1a, HIF-2a or HIF-3a) and a beta subunit called Amt. The activation of HIF by hypoxia is a multistep process involving increases in both protein stabilisation and …
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Studies into the receptor-mediated induction of hypoxia inducible factor 1α.
… and facilitates dramatic up-regulation of the protein stability and transcriptional activation capabilities of the HIF a-subunits. HIF also appears to play a role in target gene transcription in a hypoxia-independent manner. This novel, hypoxia-independent function of HIF is poorly …
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Comparative hypoxia responses and oxygen sensing in galaxiid fishes
… cells (NECs) and by the transcription protein hypoxia inducible factor 1 (HIF-1), the effect of inescapable moderate hypoxia at 5 mg L-1 dissolved oxygen concentration (without access to the water surface) on these parameters was investigated. Swimming speed decreased significantly from …