Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"protein quantitation"”.
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Emerging concepts in the pathophysiology of acute pancreatitis
… MODS might be mediated by toxic factors in the protein fraction of disease conditioned mesenteric lymph (ML). Using the advanced proteomic techniques of isobaric tags (iTRAQ™) for relative protein quantitation together with liquid chromatography–tandem mass spectrometry for the identification of …
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Structure and Function Studies on tRNA Splicing Endonuclease
… cleaves some mRNAs that encode mitochondrial proteins to initiate mRNA degradation. Interestingly, single amino acid mutations in TSEN cause the human Mendelian disease pontocerebellar hypoplasia (PCH) by an unknown mechanism. Recently, several groups have determined the structure of human …
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Fourier Transform Based Analysis of Mass Spectra: Disentangling Mass Heterogeneity and Polydispersity
… extends the reproducibility of FT/GT analysis to protein quantitation of MS imaging data from biological tissue, developing a new workflow for batch deconvolution to process tens of thousands of spectra in a few hours. The distinct protein ion patterns generated by GT simplify characterization of …
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Mass spectrometry based proteomic strategies applied in the study of central nervous system derived cells
… proteomic strategies for identification and quantitation of proteins. Development of such strategies is important to achieve a better understanding of regulatory mechanisms of individual cell types, both during normal development and during the onset and progression of diseases. Cells derived …
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Multidimensional liquid chromatographic separations for proteomics
… to reduce this complexity, both at an intact protein and digested peptide level. For complex lysates containing many thousands of proteins, orthogonal (mutually independent), multidimensional separation methods must be employed to provide sufficient resolution to characterize the appropriate …