Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"protein polymer"”.
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Self-assembly of globular protein-polymer diblock copolymers
Self-assembly of protein-polymer block copolymers provides a simple bottom-up approach towards protein nanopatteming for the fabrication of more effective and efficient bioelectronic and biocatalytic devices. Changes in shape and surface chemistry between proteinpolymer conjugates and classical …
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Predicting self-assembly in globular protein-polymer bioconjugates
Globular proteins offer powerful solutions for addressing challenges in the fields of medicine, industry, defense, and energy. Enzymes perform reactions with high efficiency and specificity, allowing for minimal generation of undesired side products even while exhibiting rapid turnover-traits …
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Synthesis and Characterization of Protein-Polymer Core-Shell Structures
<p>Proteins and bionanoparticles (BNPs) are the key building blocks of all biological matters. The study of their self-assembly behavior with various polymers is of increasing interest for development of functional materials. Compared to inorganic or organic nanoparticles, BNPs are truly …
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Driving forces of self-assembly in protein-polymer bioconjugates
Protein-polymer bioconjugates have shown great promise as high-performance biomaterials, with a diverse range of applications. Bioconjugation to a polymer allows the protein to maintain or even enhance its activity while imparting self-assembly capabilities to the overall material, which provide …
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Intrinsically Disordered Protein Polymer Libraries as Tools to Understand Protein Hydrophobicity
<p>Intrinsically disordered protein polymers (IDPPs) are repetitive biopolymers that, when enriched with prolines, glycines, and aliphatic amino acids, have observable lower critical solution temperature (LCST) phase transition behavior at physiologically relevant temperature and concentration …
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Interactions governing the self-assembly of globular protein-polymer block copolymers
Engineering enzymes and other proteins into biocatalysts or bioelectronic devices has the potential to lead to a new generation of energy-generating and energy conversion technologies. Controlling the hierarchical structure of protein materials from the nanoscale single molecule level up to the …
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Visible Light-Mediated Polymerization for Protein-Polymer Conjugation: A Biocompatible Tool for Therapeutic Applications
Proteins are natural biopolymers composed of amino acids, holding significant roles in both industry and medicine towing to their high efficiency and selectivity. Conjugating synthetic polymers to proteins results in novel hybrid macromolecular structures, which synergistically combine the benefits …
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Controlling nanostructures of globular protein-polymer block copolymers in bulk solutions and in thin films
The self-assembly of globular protein-polymer diblock copolymers represents a promising technology for protein nanopatterning. The self-assembled materials have a high density of proteins and internal nanostructures that serve as continuous transport pathways for substrates, products, cofactors, …
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Self assembled transmembrane protein polymer conjugates for the generation of nano thin membranes and micro compartments
… membranes with an embedded transmembrane protein to act as the pore. The membranes were formed by crosslinking of transmembrane protein polymer conjugates. The conjugates were self assembled on air water interface and the polymer chains crosslinked using a UV crosslinkable comonomer to …
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Elastin-like polypeptide (ELP) tags for self-assembly and high-throughput processing of functional protein materials
… and catalytic capabilities of globular proteins makes these biomolecules promising candidates in a broad array of applications, including industrial production of commodity chemicals, point-of-care diagnostics, and therapeutics. Self-assembly of globular protein-polymer bioconjugates …
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Investigating Controlled Release Pulmonary Drug Delivery Systems
… performance and dissolution profile. A hybrid protein-polymer controlled release pulmonary drug delivery system was developed to sustain the release of a water-soluble anti-asthma drug, cromolyn sodium (CS). Two excipients with complementary characteristics – a protein, bovine serum albumin, …
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Biomimetic membranes as new materials for applications in envrionmental engineering and biology
Biological water channel proteins, called aquaporins, provide selective and rapid transport of water across cell membranes. They utilize an elegant mechanism distinct from and more efficient than that used in commercial solute separation polymeric membranes such as Reverse Osmosis (RO) membranes. …
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An In Vivo histological, and In Vitro biomechanical study of nucleus replacement with a novel polymeric hydrogel
… and fusion. This thesis evaluated a novel protein polymer hydrogel composed of silk and elastin as a nucleus replacement material. There are three experimental components; one in vivo and two in vitro portions. In the first experimental portion, a large animal model was developed to …
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Molecular structure, hierarchical assembly and stimuli-responsive mechanics of tropoelastin and elastin biomaterials
The elastin polymer, assembled from its molecular precursor tropoelastin, is the dominant component of elastic fibers, which confer elasticity and structural integrity to skin, lung, connective and vascular tissue. Historically, elastin's dynamic nature has precluded traditional approaches such as …
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Plant proteins as multifunctional additives in polymer composites
… wheat gliadin, and corn zein agricultural proteins were evaluated as multifunctional additives that: (1) provided reinforcement, (2) improved thermal stability, and (3) lowered the cost of polymer composites. Wheat proteins were utilized in two polymer matrices: poly(vinyl alcohol) (PVA) …
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Supramolecular Approaches to Viscoelastic Biomaterials and Their Applications
… The extracellular matrices (ECM), or the protein-polymer scaffolds surrounding the cells in our body, possess unique tissue-dependent viscoelasticity to protect and provide mechanical queues to the nearby cells. Viscoelasticity in polymeric hydrogels can be achieved in several ways, one of …
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Self-assembly of synthetic and biological components in water using cucurbit[8]uril
… self-assembly of supramolecular block copolymers from polymeric, and small molecule building blocks. Here, end group-functionalised polymer guests were shown to assemble with small molecule ditopic guests in the presence of CB[8] to form block copolymers. Copolymers of various molecular …
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Processing Extrudable Sheets using Decoloured Bloodmeal
… bloodmeal thermoplastic (DBT), a thermoplastic protein material, with poly (lactic acid) (PLA), a semi-crystalline polymer, and subsequently processing the blend into a sheet using extrusion. Free radical grafting was used to graft itaconic anhydride onto PLA to create reactive side groups. …