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Showing 1 to 20 of 111 for “"protein phosphorylation"”.
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Protein Phosphorylation in Archaea
Protein phosphorylation constitutes an important mechanism for cellular regulation in both Eucarya and Bacteria. All living organisms evolved from a common progenitor; this implies that protein phosphorylation as a means of regulation also exists in Archaea. Previously, in the sulfur-dependent …
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Protein phosphorylation regulation in Arabidopsis
… THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Protein phosphorylation and dephosphorylation are fundamental mechanisms involved in many cell-signaling events. Coordinated actions of protein kinases and protein phosphatases help maintain the signaling through reversible protein phosphorylation …
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Metabolic Regulation of Protein Phosphorylation and Acetylation
Pages i-xviii are misnumbered in a variety of ways.
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Regulation of smooth muscle contraction by protein phosphorylation
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Manganese-stimulated protein phosphorylation in the rat pancreas.
… To investigate the effect of Mn²⁺ on pancreatic protein phosphorylation, we incubated rat pancreatic cytosol in Tris buffer (pH 7.5) with [γ-³²P] ATP. Analysis using SDS-PAGE and autoradiography revealed a single protein (p98), with a Mr of 98 kDa and a pI of 6.4 to 6.5, which was phosphorylated …
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Microfluidic Approaches for Probing Protein Phosphorylation in Cells
Protein phosphorylation plays critical roles in diverse cellular functions, including cell cycle, growth, differentiation, and apoptosis. Deregulated phospho-signaling is often associated with many human diseases and cancers. Despite tremendous efforts to investigate the molecular mechanisms that …
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The Addicted Phenotype: Protein Phosphorylation Status and Dopamine Receptor Responsiveness
… alterations in cAMP-dependent and -independent protein phosphorylation in vivo produced by chronic cocaine and heroin self-administration, changes in mesolimbic protein phosphorylation compared to individual differences in the propensity for escalating cocaine self-adminstration, and, …
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Protein phosphorylation and cell diversification in the mouse early embryo.
… of the two cell types present in the blastocyst. Protein phosphorylation is a post-translational modification believed to be important in the modulation of cell shape and cytoskeletal assembly. It is therefore feasible to propose a role for protein phosphorylation in compaction. Two types of …
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Modulation of Signal Transduction in the Nervous System by Protein Phosphorylation
… brain function. This thesis examines the role of protein phosphorylation in mediating three different molecular mechanisms by which neurotransmitter receptors transduce their signals: chemically-gated ion channels, receptor-linked ion channels and receptor-linked ion pumps. The nicotinic …
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Cytoskeletal Protein Phosphorylation in the Murine Macrophage and Its Relationship to Macrophage Activation
Made available in DSpace on 2014-12-16T06:35:39Z (GMT). No. of bitstreams: 1 8521760.pdf: 2986168 bytes, checksum: dba94e02f83309292beff25ae06763fa (MD5) Previous issue date: 1985
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Genetic and Biochemical Studies on Protein Phosphorylation in the Circadian Clock of Drosophila Melanogaster
… oscillators in all studied model systems. Protein phosphorylation plays an essential role, regulating the stability, activity and subcellular localization of proteins that constitute the biological clock. This study investigates the role of the protein kinase Doubletime, a Drosophila …
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Systemic Cytokine Expression and Endothelial Dysfunction: Insights from Innate Immune Models of Protein Phosphorylation
… their role in endothelial dysfunction. These proteins are either essential in inflammatory homeostasis (A20 binding inhibitor of NF-ĸB-1 and mitogen and stress activated kinase 1/ 2) through negative regulation of inflammation or are fundamental in the cascade for cytokines synthesis (myeloid …
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The role of protein phosphorylation in the switching between modes of synaptic vesicle release
… activation by phorbol ester of calcium-dependent protein kinase C also led to switch from a kiss-and-run mode to a full fusion mode of exocytosis. This and earlier data indicated that protein phosphorylation and calcium levels play a role in discerning the mode of synaptic vesicle exocytosis, but …
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Tyrosine-Specific Protein Phosphorylation in Cells Transformed by Rous Sarcoma Virus or Stimulated by Mitogens
The transforming proteins of several RNA tumor viruses as well as a number of membrane receptors for polypeptide growth factors possess a tyrosine-specific protein kinase activity. Genetic and biochemical evidence indicates that this enzymatic activity is involved at the early stages of oncogenic …
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Tyrosyl Protein Phosphorylation in Human Bone Cells : Its Potential Role in Mediating Fluoride Induced Osteoblast Proliferation
… by specific inhibition of a phosphotyrosyl protein phosphatase, resulting in increased steady state levels of tyrosyl phosphorylation of key cellular proteins. Cellular levels of tyrosyl phosphorylation were determined by an immunoblot detection assay in which cellular proteins were …
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Characterisation of protein phosphorylation in Arabidopsis thaliana and Chlamydomonas reinhardtii based on affinity chromatography and mass spectrometry
Reversible protein phosphorylation is of key importance for several mechanisms of life. However, the low abundance of phosphorylated proteins hinders investigations following this direction. To circumvent this problem a new method for the enrichment of phosphorylated proteins out of complex protein …
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Crosstalk of protein phosphorylation and lysine acetylation on 14-3-3 proteins and their applications in brassinosteroid signaling and photosynthesis
Protein phosphorylation and lysine acetylation are two important post-translational modifications (PTMs) in eukaryotes. However, the crosstalk between these two modifications is largely unknown. We demonstrated that both phosphorylation and lysine acetylation occurred to an Arabidopsis protein, …
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