Global ETD Search
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Showing 1 to 2 of 2 for “"protein optimization"”.
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Identification and characterization of components that overcome secretion limitations of the yeast Pichia pastoris
… system commonly used to secrete heterologous protein. Although P. pastoris is a popular host organism, secretion inefficiency continues to be a major hurdle in its ability to produce high levels of foreign protein. Optimization of cis- and trans-acting factors has greatly enhanced the …
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Protein Design at Library Scale
Recent advances in de novo protein design have made it increasingly feasibleto create proteins with novel functions, driven by rapid progress in both com- putational modeling and high-throughput experimentation. Modern tools can explore vast sequence-structure spaces and evaluate biomolecular …