Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"protein mimicking"”.
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Characterisation of the conformational landscape of the β1-adrenergic receptor and development of a strategy towards NMR studies of the protease-activated receptor 1
… (NMR) spectroscopy. The tβ1AR is a class A G-protein-coupled receptor (GPCR) and the human counterpart is an important drug target in diseases of the heart. In chapter 2, a wide range of constructs, labelling reagents and conditions were tested to make the tβ1AR accessible to 19F NMR …
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DNA-Based Mimics of Membrane Proteins Lipid-DNA Interactions Determine Function
… nanotechnology is creating synthetic constructs mimicking function of membrane proteins. These natural molecular machines function embedded in the lipid bilayer. Similar membrane attachment of DNA-based structures is achieved by modifying the nucleic acid with hydrophobic anchors, most commonly …
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New Applications for Poly(ethylene-alt-maleic anhydride)
… existing theories surrounding antifreeze glycol protein mimicking polymers. Chapter three involved the reaction of the polymer with varying amounts of hydrophobic and hydrophilic amines in order to induce their self assembly in water. The results demonstrated that when the concentration of …