Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"protein mechanism"”.
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Electric Fields: A Metric for Molecular-level Understanding of Protein Mechanisms
Determining the molecular mechanisms at the origin of protein function remains a challenge due to the complex non-covalent interactions that shape their structure. Since the non-covalent interactions arise from charge fluctuations, electric fields can be used as a tool to quantify the interactions …
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Communication & coordination between components of the ClpAP degradation machine
… the tetradecameric ClpP peptidase to degrade proteins that are damaged, unneeded, or require degradation for regulation. ClpA has two distinct, stacked rings, termed D1 and D2, constructed from hexamerization of subunits each containing two AAA+ modules. ClpA’s twelve AAA+ modules hydrolyze …
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INVESTIGATING THE BASES OF THE SPECIFICITY OF THE RESTRICTOR COMPLEX FOR THE TERMINATION OF NONCODING TRANSCRIPTION
… of the cell. Several transcription termination mechanisms act to keep the initiation of non-productive transcription in check. The Restrictor complex, composed of the adaptor protein WDR82 and the RNA-binding protein ZC3H4, suppresses processive transcription of thousands of noncoding RNAs …