Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"protein loops"”.
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Evolution of protein structure, function, and dynamics in biological systems
… respectively. Intrinsic disorder analysis at the protein domain level revealed that early protein domains were ordered and therefore, disorder is a benefit that was acquired later in evolution. In contrast, at the more granular level of protein secondary structure, we found that protein loops of …
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Building Better Backbones: Visualizations, Analyses, and Tools for Higher Quality Macromolecular Structure Models
… empowering users to improve structures.</p><p>Proteins and nucleic acids are among the most important molecules in biology, mediating the majority of biochemical processes that comprise a living organism. Therefore, these macromolecules are important targets, both for basic research to improve …
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Information-Based Torsion Angle Potential for Proteins and Applications
… alternative to physical potentials in protein structure prediction and design. As an introduction we survey the aspects and methods involved in the derivation and applicability of various statistical potentials. The statistical potential created in this work is based on a reduced …
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Investigation and application of heterochiral proteins enabled by flow-based peptide synthesis
Natural proteins are comprised primarily of (L)-amino acids. (D)-amino acids are rare in protein structures. Solid-phase peptide synthesis (SPPS) and native chemical ligation enable the total chemical synthesis of proteins. Using these techniques, it is possible to design and study polypeptides …