Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"protein immobilisation"”.
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Applications of Sortase A from Staphylococcus aureus
… probes to biological molecules, such as proteins and DNA. This method does not require any toxic reagents or harsh conditions to achieve high level of labelling, and the product could be easily isolated from the reaction mixture. This new labelling techniques could potentially improve …
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Investigations into the sensing capabilities of an electrochemical immunosensor employing polyaniline as a mediator species
… paste electrode used as a substrate for the immobilisation of antibody, and the subsequent competition assays of protein analytes. Chapter 1 is a literature review encompassing the field of electrochemical immunosensing. chapter 3 outlines work towards developing real-time imrnunosensors to …
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Switchable biological surfaces
… properties such as wettability and bio-molecule immobilisation onto self-assembled monolayers (SAMs) has many potential biological and medical applications. The aim of this project was to produce mixed biotinylated peptide monolayers that are responsive to an electric potential, thus providing a …
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Studies into solid core drug delivery system using haemoglobin as a model drug and supercritical fluid processing for encapsulation
… core drug delivery system for oral delivery of proteins using silica as core material, haemoglobin as model drug and supercritical fluid processing as encapsulation technique. Silica particles of different morphology were used as a carrier material for protein immobilisation and fatty acids …
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Towards ultrahigh-throughput phenotypic screening using microfluidic droplets and functionalised polyacrylamide beads
… between the cell and effector (the RNA or protein product) will generally act as a counter-selective pressure for that effector. Evolution also lacks foresight. In fact, evolution’s main advantage over human efforts to develop novel drugs or catalysts seems to be the sheer number of …
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Biosensor design utilizing particle-bound enzymes
… This thesis explores whether recombinant protein technology in combination with a low-cost support matrix could provide a basis for an inexpensive, simple, and robust production process for the bio-sensing element of a diagnostic that would be amenable to manufacture in resource …